Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | FDPS | P14324 | 1/20 | 0.55 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.50 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.50 |
| ▸ | ABAT | P80404 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL498989 | 0.94 | ALDH1A1 (0.64) | ALDH1A1TSHRFDPSTTRAOX1 | |
| SCHEMBL30504088 | 0.94 | ALDH1A1 (0.64) | ALDH1A1TSHRFDPSTTRAOX1 | |
| SCHEMBL36740 | 0.92 | ALDH1A1 (0.50) | ALDH1A1TSHRFDPSTTRAOX1 | |
| SCHEMBL30360260 | 0.92 | ALDH1A1 (0.50) | ALDH1A1TSHRFDPSTTRAOX1 | |
| SCHEMBL6049278 | 0.85 | XDH (0.55) | ALDH1A1TSHRTTRHPGDMAPT | |
| SCHEMBL6049277 | 0.85 | XDH (0.55) | ALDH1A1TSHRTTRHPGDMAPT | |
| SCHEMBL30540735 | 0.84 | TRPA1 (0.50) | ALDH1A1TSHRFDPSTTRHPGD | |
| SCHEMBL1620788 | 0.84 | ALDH1A1 (0.54) | ALDH1A1TSHRFDPSHPGDTDP1 | |
| SCHEMBL28589373 | 0.83 | ALDH1A1 (0.72) | ALDH1A1TSHRFDPSTTRAOX1 | |
| SCHEMBL9677313 | 0.83 | ALDH1A1 (0.72) | ALDH1A1TSHRFDPSTTRAOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025119216-A1 | BORONIC ACID β-LACTAMASE INHIBITOR, PREPARATION METHOD THEREFOR, AND USE THEREOF | 珠海联邦制药股份有限公司 | 2025-06-12 | — | — | WO | disclosed |
| US-20240238445-A1 | INHIBITORS AND USES THEREOF | NEURACLE SCIENCE CO., LTD. (KR) | 2024-07-18 | — | — | US | disclosed |
| EP-4367090-A1 | INHIBITORS AND USES THEREOF | Neuracle Science Co., Ltd. (KR) | 2024-05-15 | — | — | EP | disclosed |
| CN-117279887-A | Inhibitors and uses thereof | 纽洛可科学有限公司 | 2023-12-22 | — | — | CN | disclosed |
| US-20230137943-A1 | PHOTOPROXIMITY PROFILING OF PROTEIN-PROTEIN INTERACTIONS IN CELLS | THE UNIVERSITY OF CHICAGO | 2023-05-04 | — | — | US | disclosed |
| WO-2023281476-A1 | INHIBITORS AND USES THEREOF | NEURACLE SCIENCE CO., LTD. (KR) | 2023-01-12 | — | — | WO | disclosed |
| US-20220289657-A1 | COMPOSITION FOR PREVENTING OR TREATING BACTERIAL INFECTIOUS DISEASE COMPRISING 4-GINGEROL DERIVATIVE COMPOUND AS ACTIVE INGREDIENT | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION, SEJONG CAMPUS (KR) | 2022-09-15 | — | — | US | disclosed |
| US-11166891-B2 | Bis phenyl hexa trien derivatives, preparation method thereof, and composition for skin whitening containing the same as an active ingredient | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2021-11-09 | — | — | US | disclosed |
| US-11166891-B2 | Bis phenyl hexa trien derivatives, preparation method thereof, and composition for skin whitening containing the same as an active ingredient | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2021-11-09 | — | — | US | disclosed |
| WO-2021040333-A1 | COMPOSITION FOR PREVENTING OR TREATING BACTERIAL INFECTIOUS DISEASE COMPRISING 4-GINGEROL DERIVATIVE COMPOUND AS ACTIVE INGREDIENT | 고려대학교 세종산학협력단 | 2021-03-04 | — | — | WO | disclosed |
| EP-2194046-A1 | Triazolone derivative | Eisai R&D Management Co., Ltd. (JP) | 2010-06-09 | — | — | EP | disclosed |
| US-20100130738-A1 | PYRAZOLONE DERIVATIVE AND PDE INHIBITOR CONTAINING THE SAME AS ACTIVE INGREDIENT | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2010-05-27 | — | — | US | disclosed |
| US-20100130738-A1 | PYRAZOLONE DERIVATIVE AND PDE INHIBITOR CONTAINING THE SAME AS ACTIVE INGREDIENT | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 2010-05-27 | — | — | US | disclosed |
| EP-2168959-A1 | PYRIDAZINONE DERIVATIVE AND PDE INHIBITOR CONTAINING THE SAME AS ACTIVE INGREDIENT | Kyorin Pharmaceutical Co., Ltd. (JP) | 2010-03-31 | — | — | EP | disclosed |
| EP-2168960-A1 | PYRAZOLONE DERIVATIVE AND PDE INHIBITOR CONTAINING THE SAME AS ACTIVE INGREDIENT | Kyorin Pharmaceutical Co., Ltd. (JP) | 2010-03-31 | — | — | EP | disclosed |
| US-20100048887-A1 | COMPOUNDS INCLUDING AN ANTI-INFLAMMATORY PHARMACORE AND METHODS OF USE | REATA PHARMACEUTICALS, INC. | 2010-02-25 | — | — | US | disclosed |
| EP-2149548-A1 | METHOD FOR THE CHEMICAL SYNTHESIS OF CAPSINOIDS | Universidad De Cádiz (ES) | 2010-02-03 | — | — | EP | disclosed |
| EP-2000465-A1 | TRIAZOLONE DERIVATIVE | Eisai R&D Management Co., Ltd. (JP) | 2008-12-10 | — | — | EP | disclosed |
| US-20080015199-A1 | Triazolone derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-01-17 | — | — | US | disclosed |
| US-5861532-A | Solid-phase synthesis of N-alkyl amides | CHIRON CORPORATION (US) | 1999-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11166891-B2 | Bis phenyl hexa trien derivatives, preparation method thereof, and composition for skin whitening containing the same as an active ingredient | TYR, MITF, TPH1 | ALDH1A1 1592/4885TSHR 2021/4885FDPS 4132/4885 |
| US-20100130738-A1 | PYRAZOLONE DERIVATIVE AND PDE INHIBITOR CONTAINING THE SAME AS ACTIVE INGREDIENT | PDE3A, PDE3B, PDE2A | ALDH1A1 121/4885TSHR 2842/4885FDPS 1463/4885 |
| US-20220289657-A1 | COMPOSITION FOR PREVENTING OR TREATING BACTERIAL INFECTIOUS DISEASE COMPRISING 4-GINGEROL DERIVATIVE COMPOUND AS ACTIVE INGREDIENT | HSD11B1, GRHPR, TIPRL | ALDH1A1 3013/4885TSHR 2594/4885FDPS 290/4885 |
| US-20100048887-A1 | COMPOUNDS INCLUDING AN ANTI-INFLAMMATORY PHARMACORE AND METHODS OF USE | PTGES, PTGS1, PTGES2 | ALDH1A1 609/4885TSHR 3315/4885FDPS 1124/4885 |
| US-20230137943-A1 | PHOTOPROXIMITY PROFILING OF PROTEIN-PROTEIN INTERACTIONS IN CELLS | PPIA, S100A4, S100A6 | ALDH1A1 2889/4885TSHR 4066/4885FDPS 2079/4885 |
| US-20240238445-A1 | INHIBITORS AND USES THEREOF | FAM20C, LRRC59, PDLIM5 | ALDH1A1 4550/4885TSHR 4191/4885FDPS 3222/4885 |
| US-20080015199-A1 | Triazolone derivatives | F3, F12, F2 | ALDH1A1 710/4885TSHR 104/4885FDPS 4229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.