Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2517751 | 0.86 | MAPK1 (0.51) | NPC1RAB9ACYP1A2CYP2C19RIPK1 | |
| SCHEMBL2324520 | 0.83 | CYP1A2 (0.49) | MAPTSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL1739359 | 0.80 | L3MBTL1 (0.47) | ALDH1A1L3MBTL1 | |
| Methylene Chloride SCHEMBL6533812 | 0.80 | MAPK1 (0.47) | MAPTSMN1; SMN2NPC1RAB9ACYP1A2 | |
| SCHEMBL1738878 | 0.79 | RAB9A (0.50) | SMN1; SMN2NPC1RAB9ACYP1A2CYP3A4 | |
| SCHEMBL7669152 | 0.78 | HSD17B10 (0.41) | MAPTSMN1; SMN2TP53ALDH1A1NPSR1 | |
| SCHEMBL10169870 | 0.75 | MAPT (0.61) | MAPTSMN1; SMN2TP53ALDH1A1HPGD | |
| SCHEMBL20696983 | 0.75 | CYP2A6 (0.45) | MAPTRAB9ACYP1A2CYP3A4CYP2C19 | |
| SCHEMBL21834055 | 0.74 | NPC1 (0.54) | MAPTSMN1; SMN2NPC1RAB9AMEN1 | |
| SCHEMBL9349368 | 0.74 | CCKAR (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |