Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | FCGR1A | P12314 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | STAT1 | P42224 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2517751 | 0.94 | MAPK1 (0.51) | MAPK1KDM4CLMNANPY5RCYP1A2 | |
| SCHEMBL2324670 | 0.80 | MAPT (0.41) | MAPK1LMNACYP1A2CYP2C19NPC1 | |
| SCHEMBL1738878 | 0.77 | RAB9A (0.50) | LMNACYP1A2CYP2C19NPC1RAB9A | |
| SCHEMBL4254538 | 0.75 | ALDH1A1 (0.41) | MAPK1KDM4CLMNACYP1A2CYP2C19 | |
| SCHEMBL1739359 | 0.75 | L3MBTL1 (0.47) | L3MBTL1ALDH1A1 | |
| SCHEMBL2324520 | 0.74 | CYP1A2 (0.49) | LMNACYP1A2CYP2C19NPC1RAB9A | |
| SCHEMBL964125 | 0.74 | MAPK1 (0.66) | MAPK1CYP1A2CYP2C19FCGR1ANPC1 | |
| SCHEMBL28433874 | 0.73 | MAPK1 (0.47) | MAPK1LMNANPY5RCYP1A2CYP2C19 | |
| SCHEMBL14108176 | 0.73 | CYP1A2 (0.56) | MAPK1KDM4CLMNACYP1A2CYP2C19 | |
| SCHEMBL5106402 | 0.73 | P2RX7 (0.43) | MAPK1KDM4CLMNACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005040127-A1 | NOVEL COMPOUNDS AS AGONIST FOR PPAR GAMMA AND PPAR ALPHA, METHOD FOR PREPARATION OF THE SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | LG LIFE SCIENCES LTD. (KR) | 2005-05-06 | — | — | WO | disclosed |