Sugi Predict

Sugi Predict / Compounds / SCHEMBL10169870

SCHEMBL10169870

SCHEMBL10169870

Cc1ccc(-n2nc(C)cc2C)cc1

nearest known ligand 0.61

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 4/20 0.61
▸ ALDH1A1 P00352 3/20 0.53
▸ L3MBTL1 Q9Y468 2/20 0.53
▸ HPGD P15428 1/20 0.53
▸ AHR P35869 1/20 0.51
▸ TDP1 Q9NUW8 2/20 0.50
▸ NPSR1 Q6W5P4 2/20 0.50
▸ TP53 P04637 1/20 0.50
▸ TERT O14746 1/20 0.49
▸ LMNA P02545 2/20 0.49
▸ MAPK10 P53779 1/20 0.49
▸ KDM4E B2RXH2 1/20 0.48
▸ GAA P10253 1/20 0.48
▸ SMN1; SMN2 Q16637 2/20 0.48
▸ CASP3 P42574 1/20 0.47
▸ SENP8 Q96LD8 1/20 0.47
▸ SENP7 Q9BQF6 1/20 0.47
▸ SENP6 Q9GZR1 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29120365 0.93 MAPT (0.67) MAPTALDH1A1L3MBTL1HPGDTDP1
SCHEMBL29280344 0.85 MAPT (0.59) MAPTALDH1A1L3MBTL1HPGDAHR
SCHEMBL4515430 0.83 MAPT (0.60) MAPTALDH1A1L3MBTL1HPGDTDP1
SCHEMBL4231163 0.83 MAPT (0.59) MAPTALDH1A1L3MBTL1HPGDAHR
SCHEMBL7802727 0.83 MAPT (0.57) MAPTALDH1A1L3MBTL1HPGDAHR
SCHEMBL12770967 0.83 POLB (0.64) MAPTALDH1A1L3MBTL1HPGDNPSR1
SCHEMBL597831 0.83 MAPT (0.57) MAPTALDH1A1L3MBTL1HPGDAHR
SCHEMBL14478805 0.83 MAPT (0.57) MAPTALDH1A1L3MBTL1HPGDTDP1
SCHEMBL1353576 0.83 TERT (0.66) MAPTALDH1A1L3MBTL1HPGDTDP1
SCHEMBL964125 0.83 MAPK1 (0.66) MAPTALDH1A1L3MBTL1HPGDTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250135059-A1 COMPOSITIONS COMPRISING FRAGRANCE MATERIALS THE PROCTER & GAMBLE COMPANY 2025-05-01 — — US disclosed
US-20240336868-A1 COMPOSITIONS COMPRISING ADAMANTYL ESTER-CONTAINING COMPOUNDS THE PROCTER & GAMBLE COMPANY 2024-10-10 — — US disclosed
EP-3143026-B1 COMPOUNDS AND COMPOSITIONS FOR INDUCING CHONDROGENESIS NOVARTIS AG (CH) 2024-07-10 — — EP disclosed
CN-114292234-B Preparation method of pyrazole derivative 南方海洋科学与工程广东省实验室(湛江) 2024-05-14 — — CN disclosed
EP-3628044-B1 PYRROLO[2,3-C]PYRIDINES AND RELATED ANALOGS AS LSD-1 INHIBITORS UNIV MICHIGAN REGENTS (US) 2023-11-22 — — EP disclosed
CN-114292234-A Preparation method of pyrazole derivative 南方海洋科学与工程广东省实验室(湛江) 2022-04-08 — — CN disclosed
US-10562858-B2 Crystalline anti-trichophyton agents and preparation process thereof MEIJI SEIKA PHARMA CO., LTD. (JP) 2020-02-18 — — US disclosed
US-10562858-B2 Crystalline anti-trichophyton agents and preparation process thereof MEIJI SEIKA PHARMA CO., LTD. (JP) 2020-02-18 — — US disclosed
CN-106573892-B Crystalline anti-tinea alba bacteria medicine and preparation method thereof 明治制果药业株式会社 2019-10-25 — — CN disclosed
CN-110218187-A Crystallinity tinea alba fungi resisting medicine and preparation method thereof 明治制果药业株式会社 2019-09-10 — — CN disclosed
US-20140350006-A1 Pyrazolopyridine Derivatives, Preparation Process Therefor And Therapeutic Use Thereof SANOFI (FR) 2014-11-27 — — US disclosed
US-8637568-B2 Serotonin reuptake inhibitors THERAVANCE, INC. (US) 2014-01-28 — — US disclosed
US-20130296322-A1 SEROTONIN REUPTAKE INHIBITORS THERAVANCE, INC. (US) 2013-11-07 — — US disclosed
US-8173699-B2 Compounds for the treatment of inflammatory diseases BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2012-05-08 — — US disclosed
US-8110570-B2 Modulators of acetyl-coenzyme A carboxylase and methods of use thereof CROPSOLUTION, INC. (US) 2012-02-07 — — US disclosed
US-8110570-B2 Modulators of acetyl-coenzyme A carboxylase and methods of use thereof CROPSOLUTION, INC. (US) 2012-02-07 — — US disclosed
WO-2011021645-A1 BICYCLIC UREA DERIVATIVE OR PHARMACOLOGICALLY PERMITTED SALT THEREOF 大日本住友製薬株式会社 (JP) 2011-02-24 — — WO disclosed
US-20100190767-A1 Compounds for the treatment of inflammatory diseases ANDERSKEWITZ RALF 2010-07-29 — — US disclosed
US-20100009982-A1 Modulators of Acetyl-Coenzyme A Carboxylase and Methods of Use Thereof CROPSOLUTION, INC. 2010-01-14 — — US disclosed
US-20100009982-A1 Modulators of Acetyl-Coenzyme A Carboxylase and Methods of Use Thereof CROPSOLUTION, INC. 2010-01-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100190767-A1 Compounds for the treatment of inflammatory diseases MALT1, IL1B, RORC MAPT 2679/4885ALDH1A1 321/4885L3MBTL1 3383/4885
US-20130296322-A1 SEROTONIN REUPTAKE INHIBITORS SLC6A4, SLC6A2, TPH1 MAPT 1452/4885ALDH1A1 927/4885L3MBTL1 4661/4885
US-10562858-B2 Crystalline anti-trichophyton agents and preparation process thereof ZP1, TBKBP1, MITF MAPT 937/4885ALDH1A1 4781/4885L3MBTL1 1439/4885
US-20100009982-A1 Modulators of Acetyl-Coenzyme A Carboxylase and Methods of Use Thereof ACACA, ACAT1, ACACB MAPT 1108/4885ALDH1A1 476/4885L3MBTL1 1191/4885
US-20140350006-A1 Pyrazolopyridine Derivatives, Preparation Process Therefor And Therapeutic Use Thereof FGF1, FGF2, FGFR1 MAPT 4077/4885ALDH1A1 356/4885L3MBTL1 4849/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.