SCHEMBL13835189

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2327513	0.88	MET (0.42)	TGFBR1METPDK2FEN1
	SCHEMBL2323346	0.87	FEN1 (0.47)	TGFBR1MAP4K4METPDK2FEN1
	SCHEMBL13835252	0.86	PDK2 (0.40)	TGFBR1MAP4K4PDK2
	SCHEMBL12440239	0.86	MET (0.40)	TGFBR1MAP4K4MAPK1MET
	SCHEMBL2324722	0.86	CYP11B2 (0.40)	TGFBR1MAP4K4MAPK1FEN1
	SCHEMBL19791355	0.86	MET (0.42)	TGFBR1MAP4K4METPDK2FEN1
	SCHEMBL2325268	0.85	PDK2 (0.42)	NTRK1TGFBR1METPDK2FEN1
	SCHEMBL2325058	0.82	TGFBR1 (0.41)	TGFBR1MAP4K4MET
	SCHEMBL12524283	0.82	TGFBR1 (0.41)	NTRK1TGFBR1MAP4K4MAPK1MET
	SCHEMBL12440059	0.81	MET (0.45)	NTRK1METFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.