Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 6/20 | 0.76 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.76 |
| ▸ | PIK3CB | P42338 | 4/20 | 0.76 |
| ▸ | MTOR | P42345 | 1/20 | 0.64 |
| ▸ | SMG1 | Q96Q15 | 1/20 | 0.64 |
| ▸ | EGFR | P00533 | 1/20 | 0.63 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.58 |
| ▸ | CDK2 | P24941 | 3/20 | 0.56 |
| ▸ | GSK3B | P49841 | 3/20 | 0.56 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.56 |
| ▸ | CDK4 | P11802 | 1/20 | 0.56 |
| ▸ | FLT1 | P17948 | 2/20 | 0.56 |
| ▸ | FLT4 | P35916 | 2/20 | 0.56 |
| ▸ | KDR | P35968 | 2/20 | 0.56 |
| ▸ | SYK | P43405 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27116598 | 0.90 | PIK3CG (0.83) | PIK3CGPIK3CAPIK3CBMTORSMG1 | |
| SCHEMBL27115896 | 0.88 | PIK3CG (0.76) | PIK3CGPIK3CAPIK3CBMTORSMG1 | |
| SCHEMBL8489648 | 0.88 | PIK3CG (0.76) | PIK3CGPIK3CAPIK3CBMTORSMG1 | |
| SCHEMBL7464195 | 0.88 | PIK3CG (0.83) | PIK3CGPIK3CAPIK3CBMTORSMG1 | |
| SCHEMBL5999205 | 0.87 | PIK3CG (0.77) | PIK3CGPIK3CAPIK3CBMTORSMG1 | |
| SCHEMBL2327694 | 0.86 | PIK3CG (0.61) | PIK3CGPIK3CAPIK3CBMTORSMG1 | |
| SCHEMBL2942460 | 0.85 | PIK3CG (0.76) | PIK3CGPIK3CAPIK3CBMTORSMG1 | |
| SCHEMBL2331086 | 0.85 | PIK3CG (0.70) | PIK3CGPIK3CAPIK3CBSMG1CDK2 | |
| SCHEMBL2322043 | 0.85 | PIK3CG (0.70) | PIK3CGPIK3CAPIK3CBSMG1CDK2 | |
| SCHEMBL2939794 | 0.84 | CDK5 (0.80) | PIK3CGPIK3CAPIK3CBMTORSMG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110294810-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE AG (DE) | 2011-12-01 | — | — | US | claimed |
| EP-2356102-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS PLANT PROTECTION AGENTS | Bayer CropScience AG (DE) | 2011-08-17 | — | — | EP | claimed |
| WO-2010055114-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE SA (FR) | 2010-05-20 | — | — | WO | claimed |
| US-20110294810-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS PLANT PROTECTION AGENTS | BAYER CROPSCIENCE AG (DE) | 2011-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294810-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS PLANT PROTECTION AGENTS | PRXL2A, AZI2, PIR | PIK3CG 2330/4885PIK3CA 1630/4885PIK3CB 2136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.