Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | KIF11 | P52732 | 4/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23255281 | 0.95 | GPBAR1 (0.35) | CYP1A2METAP2RXRARXRGGPBAR1 | |
| SCHEMBL23255602 | 0.94 | RXRA (0.34) | CYP1A2METAP2RXRARXRGGPBAR1 | |
| SCHEMBL23255316 | 0.93 | CYP1A2 (0.35) | CYP1A2METAP2RXRARXRGGPBAR1 | |
| SCHEMBL23255279 | 0.93 | KIF11 (0.43) | CYP1A2METAP2KIF11CYP3A4CYP3A5 | |
| SCHEMBL23255598 | 0.89 | GPBAR1 (0.35) | CYP1A2METAP2RXRARXRGGPBAR1 | |
| SCHEMBL23255595 | 0.89 | RXRA (0.34) | CYP1A2METAP2RXRARXRGGPBAR1 | |
| SCHEMBL23255282 | 0.88 | KIF11 (0.39) | CYP1A2METAP2GPBAR1KIF11CYP3A4 | |
| SCHEMBL23255315 | 0.88 | CYP1A2 (0.35) | CYP1A2METAP2RXRARXRGGPBAR1 | |
| SCHEMBL23255585 | 0.88 | CYP3A4 (0.39) | CYP1A2METAP2GPBAR1KIF11CYP3A4 | |
| SCHEMBL21758165 | 0.87 | CYP11B2 (0.38) | CYP1A2CYP3A4SLC22A12CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3581570-B1 | CARBAZOLE-PYRIDINE-TRIFLUOROMETHYLPHENYL DERIVATIVES AND RELATED COMPOUNDS FOR USE AS TADF LUMINESCENT EMITTERS IN OLEDS | CYNORA GMBH (DE) | 2021-04-21 | — | — | EP | disclosed |