SCHEMBL2325679

SCHEMBL2325679

Nc1ccc(-c2ccc(N)c(-c3ccccc3)c2-c2cccc3ccccc23)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCZ Q05513 1/20 0.49
DHFR P00374 1/20 0.42
HSD17B10 Q99714 5/20 0.40
CA12 O43570 3/20 0.40
CA1 P00915 3/20 0.40
CA2 P00918 3/20 0.40
CA9 Q16790 3/20 0.40
CYP3A4 P08684 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
TAAR1 Q96RJ0 1/20 0.40
CDK4 P11802 1/20 0.39
CCND1 P24385 1/20 0.39
ALDH1A1 P00352 4/20 0.38
HPGD P15428 3/20 0.38
KEAP1 Q14145 2/20 0.38
TSHR P16473 2/20 0.38
CRHBP P24387 1/20 0.38
CRHR2 Q13324 1/20 0.38
NFE2L2 Q16236 1/20 0.38
ATM Q13315 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL49882 0.94 PRKCZ (0.45) PRKCZDHFRHSD17B10CA12CA1
SCHEMBL27639818 0.93 PRKCZ (0.44) PRKCZDHFRHSD17B10CA12CA1
SCHEMBL3989716 0.92 PRKCZ (0.53) PRKCZDHFRHSD17B10CA12CA1
SCHEMBL29865479 0.92 PRKCZ (0.53) PRKCZDHFRHSD17B10CA12CA1
SCHEMBL3936089 0.89 DHFR (0.44) PRKCZDHFRHSD17B10CA12CA1
SCHEMBL5778909 0.88 DHFR (0.46) DHFRHSD17B10CA12CA1CA2
SCHEMBL28223683 0.88 DHFR (0.43) PRKCZDHFRHSD17B10CA12CA1
SCHEMBL861649 0.87 PRKCZ (0.50) PRKCZDHFRHSD17B10CA12CA1
SCHEMBL1847371 0.86 ALDH1A1 (0.46) PRKCZDHFRHSD17B10CA12CA1
SCHEMBL28804444 0.85 PRKCZ (0.47) PRKCZDHFRHSD17B10CA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9620721-B2 OLEDs having high efficiency and excellent lifetime GLOBAL OLED TECHNOLOGY LLC (US) 2017-04-11 US disclosed
US-20160056409-A1 ORGANIC EL ELEMENT AND METHOD FOR MANUFACTURING SAME NATIONAL INSTITUTE FOR MATERIALS SCIENCE (JP) 2016-02-25 US disclosed
US-8795855-B2 OLEDs having high efficiency and excellent lifetime GLOBAL OLED TECHNOLOGY LLC (US) 2014-08-05 US disclosed
US-20140151676-A1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME GLOBAL OLED TECHNOLOGY LLC (US) 2014-06-05 US disclosed
CN-102131891-B Hole transport materials having a sulfur-containing group UNIVERSAL DISPLAY CORP 2014-01-29 CN disclosed
CN-102131767-B Hole transport materials containing triphenylene UNIVERSAL DISPLAY CORP 2013-08-21 CN disclosed
EP-2109898-B1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME GLOBAL OLED TECHNOLOGY LLC (US) 2011-08-17 EP disclosed
CN-102131767-A Hole transport materials containing triphenylene UNIVERSAL DISPLAY CORP 2011-07-20 CN disclosed
CN-102131891-A Hole transport materials having a sulfur-containing group UNIVERSAL DISPLAY CORP 2011-07-20 CN disclosed
EP-2109898-A1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME EASTMAN KODAK COMPANY (US) 2009-10-21 EP disclosed
US-7504163-B2 Hole-trapping materials for improved OLED efficiency EASTMAN KODAK COMPANY (US) 2009-03-17 US disclosed
WO-2008094399-A1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME EASTMAN KODAK COMPANY (US) 2008-08-07 WO disclosed
US-20080182129-A1 OLEDS HAVING HIGH EFFICIENCY AND EXCELLENT LIFETIME GLOBAL OLED TECHNOLOGY LLC 2008-07-31 US disclosed
US-20070126347-A1 OLEDS with improved efficiency EASTMAN KODAK COMPANY 2007-06-07 US disclosed
US-20060008672-A1 Hole-trapping materials for improved OLED efficiency EASTMAN KODAK COMPANY 2006-01-12 US disclosed