SCHEMBL3936089

SCHEMBL3936089

Nc1ccc(-c2ccc(N)c(-c3ccccc3)c2-c2cccc3ccccc23)c(-c2cccc3ccccc23)c1-c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DHFR P00374 1/20 0.44
ALDH1A1 P00352 5/20 0.44
HSD17B10 Q99714 3/20 0.44
KEAP1 Q14145 3/20 0.44
HPGD P15428 3/20 0.44
TSHR P16473 2/20 0.44
CYP3A4 P08684 1/20 0.44
NFE2L2 Q16236 2/20 0.43
CRHBP P24387 1/20 0.43
CRHR2 Q13324 1/20 0.43
KDM4E B2RXH2 5/20 0.41
MAPT P10636 4/20 0.41
MAPK1 P28482 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
TP53 P04637 1/20 0.41
NFKB1 P19838 1/20 0.41
NFKB2 Q00653 1/20 0.41
RELA Q04206 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28223683 0.98 DHFR (0.43) DHFRALDH1A1HSD17B10KEAP1HPGD
SCHEMBL2325679 0.89 PRKCZ (0.49) DHFRALDH1A1HSD17B10KEAP1HPGD
SCHEMBL5187265 0.89 ALDH1A1 (0.50) DHFRALDH1A1HSD17B10KEAP1HPGD
SCHEMBL5778909 0.88 DHFR (0.46) DHFRALDH1A1HSD17B10KEAP1HPGD
SCHEMBL30302654 0.87 KEAP1 (0.48) DHFRALDH1A1HSD17B10KEAP1HPGD
SCHEMBL1847371 0.87 ALDH1A1 (0.46) DHFRALDH1A1HSD17B10KEAP1HPGD
SCHEMBL714507 0.85 ALDH1A1 (0.42) DHFRALDH1A1HSD17B10KEAP1HPGD
SCHEMBL788001 0.83 ALDH1A1 (0.56) DHFRALDH1A1HSD17B10KEAP1HPGD
SCHEMBL49882 0.83 PRKCZ (0.45) DHFRALDH1A1HSD17B10KEAP1HPGD
SCHEMBL4010018 0.82 KDM4E (0.44) DHFRALDH1A1HSD17B10HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7517472-B2 Blend of viscosity modifier and luminescent compound DOW GLOBAL TECHNOLOGIES INC. (US) 2009-04-14 US disclosed
US-20060197059-A1 BLEND OF VISCOSITY MODIFIER AND LUMINESCENT COMPOUND DOW GLOBAL TECHNOLOGIES INC. 2006-09-07 US disclosed
WO-2004106458-A1 BLEND OF VISCOSITY MODIFIER AND LUMINESCENT COMPOUND DOW GLOBAL TECHNOLOGIES INC. (US) 2004-12-09 WO disclosed
US-6372154-B1 Luminescent ink for printing of organic luminescent devices CANON KABUSHIKI KAISHA (JP) 2002-04-16 US disclosed