Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | MTOR | P42345 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | PYGL | P06737 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ribose (Furanose) SCHEMBL2325834 | 0.83 | LMNA (0.49) | LMNAMTORTHRBMDM2NCOA1 | |
| Ribose (Furanose) SCHEMBL3341287 | 0.83 | LMNA (0.49) | LMNAMTORTHRBMDM2NCOA1 | |
| Ribose (Furanose) SCHEMBL142622 | 0.83 | LMNA (0.49) | LMNAMTORTHRBMDM2NCOA1 | |
| Ribose (Furanose) SCHEMBL8833 | 0.83 | LMNA (0.49) | LMNAMTORTHRBMDM2NCOA1 | |
| Ribose (Furanose) SCHEMBL628713 | 0.82 | LMNA (0.48) | LMNAMTORTHRBMDM2NCOA1 | |
| Ribose (Furanose) SCHEMBL561196 | 0.82 | LMNA (0.48) | LMNAMTORTHRBMDM2NCOA1 | |
| SCHEMBL20718 | 0.74 | — | — | |
| Ribose (Furanose) SCHEMBL20917249 | 0.69 | AXL (0.57) | PYGL | |
| Ribose (Furanose) SCHEMBL5139187 | 0.68 | PYGL (0.47) | PYGL | |
| Ribose (Furanose) SCHEMBL27934652 | 0.68 | PYGL (0.47) | PYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-10036386-A | — | — | None | — | — | JP | disclosed |
| JP-10036383-A | — | — | None | — | — | JP | disclosed |
| JP-10036385-A | — | — | None | — | — | JP | disclosed |
| JP-10036384-A | — | — | None | — | — | JP | disclosed |
| JP-9301992-A | — | — | None | — | — | JP | disclosed |
| JP-H1036383-A | 4-N-ACYL-2-THIOCYTOSINE ARABINOSIDE AND ANTICANCER AGENT CONTAINING THE COMPOUND AS ACTIVE INGREDIENT | TOAGOSEI CO LTD | 1998-02-10 | — | — | JP | disclosed |
| JP-H1036386-A | 4-N-ACYL-2-THIOCYTOSINE ARABINOSIDE AND ANTICANCER AGENT CONTAINING THE COMPOUND AS ACTIVE INGREDIENT | TOAGOSEI CO LTD | 1998-02-10 | — | — | JP | disclosed |
| JP-H1036385-A | 4-N-ACYL-2-THIOCYTOSINE ARABINOSIDE AND ANTICANCER AGENT CONTAINING THE COMPOUND AS ACTIVE INGREDIENT | TOAGOSEI CO LTD | 1998-02-10 | — | — | JP | disclosed |
| JP-H1036384-A | 4-N-ACYL-2-THIOCYTOSINE ARABINOSIDE AND ANTICANCER AGENT CONTAINING THE COMPOUND AS ACTIVE INGREDIENT | TOAGOSEI CO LTD | 1998-02-10 | — | — | JP | disclosed |
| JP-H09301992-A | 2-THIOCYTOSINE ARABINOSIDE DERIVATIVES AND RPOCUTION OF THE SAME OR 2-THIOCYTOSINE ARABINOSIDE | TOAGOSEI CO LTD | 1997-11-25 | — | — | JP | disclosed |