Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.58 |
| ▸ | P4HB | P07237 | 5/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | RELA | Q04206 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11038651 | 0.84 | CA12 (0.57) | CHRNA7P4HBNR1H4ABCG2CA12 | |
| SCHEMBL1348921 | 0.81 | GPR52 (0.56) | PARP1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL11813977 | 0.81 | GPR52 (0.56) | PARP1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL11813974 | 0.81 | GPR52 (0.56) | PARP1MEN1MAPTKMT2AALDH1A1 | |
| SCHEMBL5646420 | 0.80 | MAPT (0.69) | CHRNA7P4HBNR1H4BCHEMAPT | |
| SCHEMBL5646424 | 0.80 | MAPT (0.69) | CHRNA7P4HBNR1H4BCHEMAPT | |
| SCHEMBL14416843 | 0.79 | SNCA (0.53) | CA12CA1CA2CA9MEN1 | |
| SCHEMBL29273761 | 0.79 | ALDH1A1 (0.68) | CHRNA7PARP1MEN1MAPTKMT2A | |
| SCHEMBL29273753 | 0.79 | CES2 (0.57) | PARP1NPC1MAPTRELARAB9A | |
| SCHEMBL30641511 | 0.79 | CES2 (0.57) | PARP1NPC1MAPTRELARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210115007-A1 | STREPTOCOCCUS MUTANS GLUCOSYL TRANSFERASE INHIBITORS FOR DENTAL CARIES THERAPY | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210115007-A1 | STREPTOCOCCUS MUTANS GLUCOSYL TRANSFERASE INHIBITORS FOR DENTAL CARIES THERAPY | UGGT1, UGCG, GLA | CHRNA7 4756/4885P4HB 2712/4885NR1H4 4098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.