Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.57 |
| ▸ | BCHE | P06276 | 4/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CHKA | P35790 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23258819 | 0.94 | ACHE (0.57) | ACHEBCHECYP1A2LMNAESR1 | |
| SCHEMBL1127774 | 0.81 | ACHE (0.85) | ACHEBCHE | |
| SCHEMBL19102953 | 0.79 | ACHE (0.56) | ACHEBCHECYP1A2LMNAALDH1A1 | |
| Bromide SCHEMBL23535338 | 0.79 | ACHE (0.60) | ACHEBCHELMNAALDH1A1CHKA | |
| Hydrochloric Acid SCHEMBL8870693 | 0.79 | ACHE (0.81) | ACHEBCHELMNA | |
| Bromide SCHEMBL3601825 | 0.79 | ACHE (0.89) | ACHEBCHE | |
| SCHEMBL23259284 | 0.78 | BCHE (0.50) | ACHEBCHECYP1A2LMNAF2 | |
| SCHEMBL19102924 | 0.75 | ACHE (0.50) | ACHEBCHECYP1A2LMNAALDH1A1 | |
| SCHEMBL8085263 | 0.72 | LMNA (0.61) | ACHEBCHECYP1A2LMNANPSR1 | |
| Bromide SCHEMBL6981181 | 0.70 | LMNA (0.59) | ACHEBCHECYP1A2LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11459323-B2 | Monocyclic β-lactam compound for treating bacterial infection | MEDSHINE DISCOVERY INC. (CN) | 2022-10-04 | — | — | US | disclosed |
| US-20210115035-A1 | MONOCYCLIC B-LACTAM COMPOUND FOR TREATING BACTERIAL INFECTION | Shenzhen Optimum Biological Technology Co., Ltd (CN) | 2021-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11459323-B2 | Monocyclic β-lactam compound for treating bacterial infection | PEPD, COASY, MRPL21 | ACHE 130/4885BCHE 30/4885CYP1A2 360/4885 |
| US-20210115035-A1 | MONOCYCLIC B-LACTAM COMPOUND FOR TREATING BACTERIAL INFECTION | COASY, BCAT2, PEPD | ACHE 320/4885BCHE 4/4885CYP1A2 256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.