Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 2/20 | 0.51 |
| ▸ | NAMPT | P43490 | 3/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.42 |
| ▸ | GRM1 | Q13255 | 8/20 | 0.39 |
| ▸ | GRM5 | P41594 | 7/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CDK7 | P50613 | 1/20 | 0.38 |
| ▸ | CDK13 | Q14004 | 1/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23259228 | 0.87 | NAMPT (0.46) | QDPRNAMPTPDK4GRM1GRM5 | |
| SCHEMBL23258524 | 0.78 | ACMSD (0.38) | — | |
| SCHEMBL23259206 | 0.74 | QDPR (0.47) | QDPRNAMPT | |
| SCHEMBL14496802 | 0.73 | QDPR (0.70) | QDPRNAMPTALOX15 | |
| SCHEMBL23258874 | 0.73 | ELANE (0.45) | BRD4 | |
| SCHEMBL23258886 | 0.71 | ELANE (0.35) | — | |
| SCHEMBL8912847 | 0.71 | NAMPT (0.63) | NAMPTPDK4GRM1GRM5CDK7 | |
| SCHEMBL3034673 | 0.71 | NAMPT (0.59) | QDPRNAMPTPDK4GRM1GRM5 | |
| SCHEMBL14340513 | 0.71 | QDPR (0.67) | QDPRNAMPTBRD4SUV39H2ALOX15 | |
| SCHEMBL27018501 | 0.71 | ELANE (0.47) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076938-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | Ambys Medicines, Inc. (US) | 2021-04-22 | — | — | WO | disclosed |