SCHEMBL23259385

SCHEMBL23259385

CC(=O)Nc1ccc(N=Nc2ccccc2C)cc1C

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.64
MAPT P10636 4/20 0.64
MEN1 O00255 4/20 0.64
ALDH1A1 P00352 2/20 0.64
LMNA P02545 1/20 0.64
AHR P35869 1/20 0.62
NPC1 O15118 4/20 0.60
HTT P42858 1/20 0.60
HPGD P15428 1/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
TSHR P16473 2/20 0.54
CYP3A4 P08684 2/20 0.54
TP53 P04637 1/20 0.54
MAPK1 P28482 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
RAB9A P51151 3/20 0.45
SIGMAR1 Q99720 3/20 0.44
THRB P10828 1/20 0.43
POLB P06746 1/20 0.42
EPHX1 P07099 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26104727 1.00 KMT2A (0.64) KMT2AMAPTMEN1ALDH1A1LMNA
SCHEMBL14612980 0.89 AHR (0.62) KMT2AMAPTMEN1ALDH1A1LMNA
SCHEMBL13609820 0.88 AHR (0.58) KMT2AMAPTMEN1ALDH1A1LMNA
SCHEMBL14130404 0.86 AHR (0.66) KMT2AMAPTMEN1ALDH1A1LMNA
SCHEMBL14130007 0.86 AHR (0.66) KMT2AMAPTMEN1ALDH1A1LMNA
SCHEMBL14582011 0.85 AHR (0.58) KMT2AMAPTMEN1ALDH1A1LMNA
SCHEMBL14130403 0.84 AHR (0.64) KMT2AMAPTMEN1ALDH1A1LMNA
SCHEMBL20762595 0.81 AHR (0.66) KMT2AMAPTMEN1ALDH1A1LMNA
SCHEMBL14582010 0.81 AHR (0.60) KMT2AMAPTMEN1ALDH1A1LMNA
SCHEMBL20762684 0.80 AHR (0.59) KMT2AMAPTMEN1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024234393-A1 FLEXIBLE INTELLIGENT WOOD HAVING RESPONSE FUNCTION, ACTUATOR, AND MANUFACTURING METHOD 南京林业大学 2024-11-21 WO claimed
US-20240383170-A1 FLEXIBLE AND SMART WOOD WITH RESPONSIVE FUNCTION, PREPARATION METHOD THEREOF AND ACTUATOR NANJING FORESTRY UNIVERSITY (CN) 2024-11-21 US claimed
CN-116373056-B Flexible intelligent wood with responsiveness function, actuator and preparation method 南京林业大学 2023-12-12 CN claimed
CN-116373056-A Flexible intelligent wood with responsiveness function, actuator and preparation method 南京林业大学 2023-07-04 CN claimed
WO-2024234393-A1 FLEXIBLE INTELLIGENT WOOD HAVING RESPONSE FUNCTION, ACTUATOR, AND MANUFACTURING METHOD 南京林业大学 2024-11-21 WO disclosed
US-20240383170-A1 FLEXIBLE AND SMART WOOD WITH RESPONSIVE FUNCTION, PREPARATION METHOD THEREOF AND ACTUATOR NANJING FORESTRY UNIVERSITY (CN) 2024-11-21 US disclosed
US-20240268136-A1 QUANTUM DOT LIGHT-EMITTING DEVICE AND METHOD FOR PATTERNING QUANTUM DOT LAYER Beijing Boe Technology Development Co., Ltd. (CN) 2024-08-08 US disclosed
WO-2023178604-A1 QUANTUM DOT LIGHT-EMITTING DEVICE AND QUANTUM DOT LAYER PATTERNING METHOD 京东方科技集团股份有限公司 2023-09-28 WO disclosed
US-20210115489-A1 NOVEL MEDIATOR KIKKOMAN CORPORATION (JP) 2021-04-22 US disclosed
CN-108273478-B Formaldehyde removal composition and product 李怀玉 2021-03-02 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210115489-A1 NOVEL MEDIATOR MPO, EPX, LPO KMT2A 3104/4885MAPT 4015/4885MEN1 2351/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.