SCHEMBL30914166

SCHEMBL30914166

CC(C)(C)OC(=O)Nc1ccccc1/C(N)=N\O

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.50
LMNA P02545 1/20 0.45
POLB P06746 1/20 0.45
RAB9A P51151 3/20 0.43
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
NPC1 O15118 2/20 0.43
HTT P42858 1/20 0.43
IDO1 P14902 1/20 0.42
METAP1 P53582 1/20 0.42
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
BRD9 Q9H8M2 1/20 0.40
HPGD P15428 1/20 0.40
GAA P10253 1/20 0.38
F10 P00742 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30914162 1.00 RXFP1 (0.50) RXFP1LMNAPOLBRAB9AKMT2A
SCHEMBL23259553 1.00 RXFP1 (0.50) RXFP1LMNAPOLBRAB9AKMT2A
SCHEMBL7540602 0.85 KDM4E (0.55) RXFP1LMNAPOLBRAB9AKMT2A
SCHEMBL30914161 0.82 RXFP1 (0.52) RXFP1LMNAPOLBRAB9AKMT2A
SCHEMBL23259552 0.82 RXFP1 (0.52) RXFP1LMNAPOLBRAB9AKMT2A
SCHEMBL29702265 0.80 RXFP1 (0.55) RXFP1LMNAPOLBRAB9AKMT2A
SCHEMBL222446 0.80 RXFP1 (0.55) RXFP1LMNAPOLBRAB9AKMT2A
SCHEMBL29992092 0.80 RXFP1 (0.59) RXFP1LMNAPOLBRAB9AKMT2A
SCHEMBL29663621 0.80 RXFP1 (0.55) RXFP1LMNAPOLBRAB9AKMT2A
SCHEMBL15368377 0.80 RXFP1 (0.59) RXFP1LMNAPOLBRAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4634160-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF Certa Therapeutics Pty Ltd (AU) 2025-10-22 EP disclosed
WO-2024124279-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF CERTA THERAPEUTICS PTY LTD (AU) 2024-06-20 WO disclosed
US-20240139190-A1 NOVEL ANTIPARASITIC COMPOUNDS AND METHODS THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2024-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240139190-A1 NOVEL ANTIPARASITIC COMPOUNDS AND METHODS TUBB, TUBB1, TUBA1C RXFP1 4761/4885LMNA 1503/4885POLB 135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.