Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.48 |
| ▸ | RXRG | P48443 | 2/20 | 0.48 |
| ▸ | RXRB | P28702 | 1/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | RGS12 | O14924 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | THPO | P40225 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29180205 | 0.80 | RXRA (0.55) | RXRARXRGRXRBSLC22A12KDM4E | |
| SCHEMBL20315028 | 0.80 | HPGD (0.50) | KDM4EHPGDHSD17B10MAPTGAA | |
| SCHEMBL18179360 | 0.78 | CYP2A6 (0.44) | KDM4EHPGDMAPTTSHRLMNA | |
| SCHEMBL4945325 | 0.77 | GAA (0.61) | KDM4EHPGDHSD17B10MAPTGAA | |
| SCHEMBL21566201 | 0.77 | KDM4E (0.47) | RXRARXRGRXRBSLC22A12KDM4E | |
| SCHEMBL13571375 | 0.77 | LOXL2 (0.42) | KDM4EALDH1A1 | |
| SCHEMBL28248932 | 0.77 | MAOB (0.36) | SLC22A12KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL11813521 | 0.77 | CYP11B1 (0.37) | KDM4ETDP1 | |
| SCHEMBL28248977 | 0.77 | MAOB (0.36) | KDM4EHPGDHSD17B10TSHRALDH1A1 | |
| SCHEMBL2731330 | 0.76 | FFAR1 (0.48) | RXRARXRGRXRBSLC22A12KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210112808-A1 | OVERPOWERED ABA RECEPTOR AGONISTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210112808-A1 | OVERPOWERED ABA RECEPTOR AGONISTS | BROX, AVPR1A, NPBWR1 | RXRA 319/4885RXRG 255/4885RXRB 348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.