Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.50 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.50 |
| ▸ | QDPR | P09417 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23249954 | 0.80 | NAMPT (0.50) | S1PR1S1PR3PPARGPPARA | |
| SCHEMBL14080907 | 0.76 | QDPR (0.53) | S1PR1S1PR3QDPRPPARGPPARA | |
| SCHEMBL14048608 | 0.74 | QDPR (0.60) | QDPRPPARGPPARA | |
| SCHEMBL13778710 | 0.73 | DRD2 (0.54) | LMNAMEN1KMT2A | |
| SCHEMBL13898494 | 0.71 | QDPR (0.68) | QDPRNPC1RAB9AKDM4ELMNA | |
| SCHEMBL50923 | 0.71 | QDPR (0.67) | QDPRNPC1RAB9AKDM4ELMNA | |
| SCHEMBL16594362 | 0.71 | TSHR (0.56) | NPC1RAB9ALTA4HKDM4ELMNA | |
| SCHEMBL16862164 | 0.71 | QDPR (0.67) | QDPRNPC1RAB9AKDM4ELMNA | |
| SCHEMBL8194797 | 0.70 | S1PR1 (0.64) | S1PR1S1PR3PPARGPPARAHRH3 | |
| SCHEMBL26567134 | 0.70 | L3MBTL1 (0.69) | LTA4HMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021077010-A1 | BIFUNCTIONAL MOLECULES CONTAINING AN E3 UBIQUITINE LIGASE BINDING MOIETY LINKED TO A BCL6 TARGETING MOIETY | ARVINAS OPERATIONS, INC. (US) | 2021-04-22 | — | — | WO | disclosed |