SCHEMBL2327258

SCHEMBL2327258

Brc1ccc2c(c1)c1cc(Br)ccc1n2C1CCCCO1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.46
MAPK1 P28482 3/20 0.43
TP53 P04637 2/20 0.43
ALDH1A1 P00352 2/20 0.43
LMNA P02545 1/20 0.43
HTT P42858 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
RXRG P48443 1/20 0.36
BAX Q07812 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
ALOX15 P16050 2/20 0.35
CYP3A4 P08684 1/20 0.35
KMT2A Q03164 4/20 0.33
MEN1 O00255 3/20 0.33
CNR2 P34972 1/20 0.33
PPARG P37231 1/20 0.33
NCOA2 Q15596 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8540288 0.84 DDB1 (0.36) MAPTMAPK1TP53ALDH1A1LMNA
SCHEMBL27241687 0.81 CYP4F2 (0.36) RXRARXRBRXRGCNR2
SCHEMBL30182911 0.79 MAPT (0.38) MAPTMAPK1TP53ALDH1A1LMNA
SCHEMBL5026596 0.77 CYP1A2 (0.41) ALDH1A1NPSR1SIGMAR1KMT2AMEN1
SCHEMBL19051094 0.77 RXRA (0.38) MAPTLMNARXRARXRBRXRG
SCHEMBL24268653 0.76 MAPT (0.37) MAPTMAPK1TP53ALDH1A1LMNA
SCHEMBL767404 0.76 CYP4F2 (0.39) MAPTMAPK1TP53ALDH1A1LMNA
SCHEMBL18281904 0.76 GAA (0.41) MAPTMAPK1TP53ALDH1A1LMNA
SCHEMBL30615352 0.76 MAPT (0.37) MAPTMAPK1TP53ALDH1A1LMNA
SCHEMBL15744178 0.76 CYP4F2 (0.39) MAPTMAPK1TP53ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240190901-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-06-13 US disclosed
US-11818948-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-14 US disclosed
US-11818948-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-14 US disclosed
US-20170186970-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2017-06-29 US disclosed
US-20170186970-A1 Organic Electroluminescent Materials and Devices UNIVERSAL DISPLAY CORPORATION 2017-06-29 US disclosed
EP-2356168-B1 AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS SOLVAY USA INC (US) 2015-05-27 EP disclosed
EP-2356168-B1 AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS SOLVAY USA INC (US) 2015-05-27 EP disclosed
US-20130075670-A1 AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS PLEXTRONICS, INC. (US) 2013-03-28 US disclosed
US-20130075670-A1 AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS PLEXTRONICS, INC. (US) 2013-03-28 US disclosed
US-20130075670-A1 AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS PLEXTRONICS, INC. (US) 2013-03-28 US disclosed
US-8283002-B2 Aminobenzene compositions and related devices and methods PLEXTRONICS, INC. (US) 2012-10-09 US disclosed
US-8283002-B2 Aminobenzene compositions and related devices and methods PLEXTRONICS, INC. (US) 2012-10-09 US disclosed
US-8283002-B2 Aminobenzene compositions and related devices and methods PLEXTRONICS, INC. (US) 2012-10-09 US disclosed
EP-2356168-A2 AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS Plextronics, Inc. (US) 2011-08-17 EP disclosed
US-20100292399-A1 AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS PLEXTRONICS, INC. 2010-11-18 US disclosed
US-20100292399-A1 AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS PLEXTRONICS, INC. 2010-11-18 US disclosed
US-20100292399-A1 AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS PLEXTRONICS, INC. 2010-11-18 US disclosed
WO-2010059646-A2 AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS PLEXTRONICS, INC. (US) 2010-05-27 WO disclosed
WO-2010059646-A2 AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS PLEXTRONICS, INC. (US) 2010-05-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240190901-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ODC1 MAPT 477/4885MAPK1 3088/4885TP53 3080/4885
US-20130075670-A1 AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS HLA-B, AAAS, SLCO2B1 MAPT 322/4885MAPK1 826/4885TP53 691/4885
US-20170186970-A1 Organic Electroluminescent Materials and Devices SLCO4C1, SLC29A1, SLC29A2 MAPT 3388/4885MAPK1 2012/4885TP53 2308/4885
US-11818948-B2 Organic electroluminescent materials and devices SLCO4C1, SLC29A1, SLC29A2 MAPT 3388/4885MAPK1 2012/4885TP53 2308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.