Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.59 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.59 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2327788 | 1.00 | MTNR1A (0.59) | MTNR1AMTNR1BF10PRSS1ATM | |
| SCHEMBL1709763 | 0.85 | MTNR1A (0.64) | MTNR1AMTNR1BCYP1A2KMT2ACTRB1 | |
| SCHEMBL4240995 | 0.84 | F10 (0.47) | F10PRSS1ATMCYP1A2POLB | |
| SCHEMBL23792351 | 0.84 | F10 (0.53) | F10PRSS1ATMCYP1A2POLB | |
| SCHEMBL1187483 | 0.84 | TRPM8 (0.53) | F10PRSS1CYP1A2CTRB1ALDH1A1 | |
| SCHEMBL1828061 | 0.83 | ALDH1A1 (0.43) | MTNR1AMTNR1BF10PRSS1KMT2A | |
| SCHEMBL13816316 | 0.81 | SYK (0.56) | F10PRSS1ATMCA12CA7 | |
| SCHEMBL117431 | 0.80 | CYP1A2 (0.60) | ATMCYP1A2POLBKMT2AALDH1A1 | |
| SCHEMBL3596338 | 0.80 | ALDH1A1 (0.57) | ATMCYP1A2POLBKMT2AALDH1A1 | |
| SCHEMBL20021560 | 0.80 | MTNR1A (0.57) | MTNR1AMTNR1BCYP1A2CTRB1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2534161-A1 | ENANTIOMERICALLY ENRICHED AMINODIPHOSPHINES AS LIGANDS FOR THE PREPARATION OF CATALYSTS FOR ASYMMETRIC SYNTHESIS | Enantia, S.L. (ES) | 2012-12-19 | — | — | EP | disclosed |
| US-20120309997-A1 | Enantiomerically Enriched Aminodiphosphines as Ligands for the Preparation of Catalysts for Asymmetric Synthesis | ENANTIA, S.L. (ES) | 2012-12-06 | — | — | US | disclosed |
| WO-2011098160-A1 | ENANTIOMERICALLY ENRICHED AMINODIPHOSPHINES AS LIGANDS FOR THE PREPARATION OF CATALYSTS FOR ASYMMETRIC SYNTHESIS | ENANTIA, S.L. (ES) | 2011-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309997-A1 | Enantiomerically Enriched Aminodiphosphines as Ligands for the Preparation of Catalysts for Asymmetric Synthesis | PHOSPHO1, AASDHPPT, AGPS | MTNR1A 3976/4885MTNR1B 4076/4885F10 4464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.