Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.41 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.39 |
| ▸ | CCNC | P24863 | 2/20 | 0.39 |
| ▸ | CDK8 | P49336 | 2/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 1/20 | 0.38 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.38 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 2/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22886304 | 0.81 | CYP2A6 (0.55) | DYRK1AUHRF1MAPK14MAPK1CYP2A6 | |
| SCHEMBL28051935 | 0.79 | KDM4E (0.51) | DYRK1AUHRF1MAPK14CCNCCDK8 | |
| SCHEMBL28829364 | 0.76 | MAP4K4 (0.44) | DYRK1AUHRF1MAPK14MAP4K4MAPK1 | |
| SCHEMBL19961426 | 0.75 | CYP11B1 (0.44) | DYRK1AMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL31092839 | 0.73 | HDAC8 (0.45) | MAPK14MAPK1CYP2A6MTOR | |
| SCHEMBL29249875 | 0.73 | HDAC8 (0.45) | MAPK14MAPK1CYP2A6MTOR | |
| SCHEMBL1896511 | 0.73 | DYRK1A (0.65) | DYRK1ANFATC1UHRF1CCNCCDK8 | |
| SCHEMBL30308690 | 0.73 | DYRK1A (0.65) | DYRK1ANFATC1UHRF1CCNCCDK8 | |
| SCHEMBL5700281 | 0.72 | KDM4E (0.47) | TDO2CYP2A6MTOR | |
| SCHEMBL12145551 | 0.72 | WNT3A (0.51) | DYRK1AUHRF1MAPK1IRAK4CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10988447-B2 | Bipyridine derivatives and their uses for organic light emitting diodes | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2021-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10988447-B2 | Bipyridine derivatives and their uses for organic light emitting diodes | CRY2, CRY1, CCNA1 | DYRK1A 4107/4885NFATC1 4795/4885UHRF1 2184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.