Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | KLK7 | P49862 | 2/20 | 0.41 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | TGM2 | P21980 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30029104 | 1.00 | MEN1 (0.45) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL30030056 | 0.92 | TDP1 (0.47) | MEN1KMT2AGAAALDH1A1KLK7 | |
| SCHEMBL29796125 | 0.86 | CAPN1 (0.46) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL14439650 | 0.85 | ALDH1A1 (0.46) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL15888952 | 0.85 | ALDH1A1 (0.46) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL15498945 | 0.85 | CAPN1 (0.47) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL30895514 | 0.85 | ALB (0.43) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL15625939 | 0.84 | ALDH1A1 (0.46) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL14674508 | 0.84 | ALDH1A1 (0.46) | MEN1KMT2AGAAALDH1A1TSHR | |
| SCHEMBL16013190 | 0.84 | TGM2 (0.43) | TGM2FOLH1ITGB3ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3070095-B1 | ADENO-ASSOCIATED VIRUS WITH SITE-DIRECTED MUTAGENESIS AND SITE-DIRECTED MODIFICATION, AND PREPARATION METHOD AND APPLICATION THEREFOR | UNIV BEIJING (CN) | 2021-04-28 | — | — | EP | disclosed |