Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 6/20 | 0.42 |
| ▸ | CTSS | P25774 | 3/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | ALB | P02768 | 4/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 2/20 | 0.38 |
| ▸ | KLK7 | P49862 | 1/20 | 0.38 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14674508 | 1.00 | ALDH1A1 (0.46) | ALDH1A1TSHRMEN1GAAKMT2A | |
| SCHEMBL14682796 | 0.91 | TDP1 (0.45) | ALDH1A1MEN1KMT2ACTSKCTSS | |
| SCHEMBL29796125 | 0.90 | CAPN1 (0.46) | ALDH1A1TSHRMEN1GAAKMT2A | |
| SCHEMBL15498945 | 0.89 | CAPN1 (0.47) | ALDH1A1TSHRMEN1GAAKMT2A | |
| SCHEMBL21602728 | 0.87 | CAPN1 (0.46) | ALDH1A1TSHRMEN1GAAKMT2A | |
| SCHEMBL23278802 | 0.84 | MEN1 (0.45) | ALDH1A1TSHRMEN1GAAKMT2A | |
| SCHEMBL30029104 | 0.84 | MEN1 (0.45) | ALDH1A1TSHRMEN1GAAKMT2A | |
| SCHEMBL30895514 | 0.84 | ALB (0.43) | ALDH1A1TSHRMEN1GAAKMT2A | |
| SCHEMBL14439650 | 0.84 | ALDH1A1 (0.46) | ALDH1A1TSHRMEN1GAAKMT2A | |
| SCHEMBL15888952 | 0.84 | ALDH1A1 (0.46) | ALDH1A1TSHRMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240409672-A1 | MODIFIED ALGINATES AND METHODS OF MAKING AND USING THEREOF | NATIONAL INSTITUTES OF HEALTH | 2024-12-12 | — | — | US | disclosed |
| EP-4422691-A1 | MODIFIED ALGINATES AND METHODS OF MAKING AND USING THEREOF | North Carolina State University (US) | 2024-09-04 | — | — | EP | disclosed |
| CN-118434448-A | Modified alginates and methods of making and using the same | 北卡罗来纳大学 | 2024-08-02 | — | — | CN | disclosed |
| WO-2023077112-A1 | MODIFIED ALGINATES AND METHODS OF MAKING AND USING THEREOF | NORTH CAROLINA STATE UNIVERSITY (US) | 2023-05-04 | — | — | WO | disclosed |
| US-10253345-B2 | Cell lines | MEDIMMUNE LIMITED (GB) | 2019-04-09 | — | — | US | disclosed |
| EP-2898085-B1 | CELL LINES | MEDIMMUNE LTD (GB) | 2019-01-23 | — | — | EP | disclosed |
| US-20170306381-A1 | CELL LINES | ALLOZYNE, INC. | 2017-10-26 | — | — | US | disclosed |
| US-20170306380-A1 | AMINO ACID DERIVATIVES | MEDIMMUNE LIMITED (GB) | 2017-10-26 | — | — | US | disclosed |
| WO-2014044873-A1 | AMINO ACID DERIVATIVES | ALLOZYNE, INC (US) | 2014-03-27 | — | — | WO | disclosed |
| WO-2014044872-A1 | CELL LINES | ALLOZYNE, INC (US) | 2014-03-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10253345-B2 | Cell lines | AARS1, LARS1, IARS1 | ALDH1A1 4751/4885TSHR 563/4885MEN1 2150/4885 |
| US-20170306381-A1 | CELL LINES | AARS1, LARS1, IARS1 | ALDH1A1 4751/4885TSHR 563/4885MEN1 2150/4885 |
| US-20170306380-A1 | AMINO ACID DERIVATIVES | BCAT2, DNPEP, BCAT1 | ALDH1A1 2753/4885TSHR 1443/4885MEN1 2550/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.