Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 10/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.42 |
| ▸ | ALB | P02768 | 5/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17411108 | 0.91 | ACHE (0.37) | TGM2FOLH1 | |
| SCHEMBL16013473 | 0.87 | ACHE (0.40) | TGM2SIRT2SIRT1 | |
| SCHEMBL17411215 | 0.87 | ACHE (0.40) | TGM2SIRT2SIRT1 | |
| SCHEMBL23278802 | 0.84 | MEN1 (0.45) | TGM2FOLH1ALBITGB3 | |
| SCHEMBL16013191 | 0.84 | ACHE (0.32) | TGM2FOLH1 | |
| SCHEMBL30029104 | 0.84 | MEN1 (0.45) | TGM2FOLH1ALBITGB3 | |
| SCHEMBL27446533 | 0.84 | ACHE (0.43) | TGM2SIRT2SIRT1 | |
| SCHEMBL16446646 | 0.84 | DDAH1 (0.42) | — | |
| SCHEMBL18532395 | 0.83 | ACHE (0.39) | ALB | |
| SCHEMBL16013082 | 0.82 | ACHE (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2964224-B1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | POLYACTIVA PTY LTD (AU) | 2024-07-03 | — | — | EP | disclosed |
| US-10758626-B2 | Polymer conjugate comprising a bioactive agent | POLYACTIVA PTY LTD (AU) | 2020-09-01 | — | — | US | disclosed |
| US-10111886-B2 | Polymer conjugate for delivery of a bioactive agent | POLYACTIVA PTY LTD (AU) | 2018-10-30 | — | — | US | disclosed |
| US-10113033-B2 | Polymer conjugate for delivery of a bioactive agent | POLYACTIVA PTY LTD (AU) | 2018-10-30 | — | — | US | disclosed |
| US-20180303948-A1 | POLYMER CONJUGATE COMPRISING A BIOACTIVE AGENT | POLYACTIVA PTY LTD (AU) | 2018-10-25 | — | — | US | disclosed |
| US-20170216308-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | POLYACTIVA PTY LTD (AU) | 2017-08-03 | — | — | US | disclosed |
| US-20170182173-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | POLYACTIVA PTY LTD (AU) | 2017-06-29 | — | — | US | disclosed |
| US-9572892-B2 | Polymer conjugate for delivery of a bioactive agent | POLYACTIVA PTY LTD (AU) | 2017-02-21 | — | — | US | disclosed |
| EP-2964224-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | Polyactiva Pty Ltd (AU) | 2016-01-13 | — | — | EP | disclosed |
| US-20160000929-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | POLYACTIVA PTY LTD (AU) | 2016-01-07 | — | — | US | disclosed |
| WO-2014134689-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | POLYACTIVA PTY LTD (AU) | 2014-09-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10113033-B2 | Polymer conjugate for delivery of a bioactive agent | PTGIS, PTGIR, PGF | TGM2 754/4885FOLH1 962/4885ALB 4760/4885 |
| US-10758626-B2 | Polymer conjugate comprising a bioactive agent | MSN, PAM, PARG | TGM2 3656/4885FOLH1 3363/4885ALB 2843/4885 |
| US-10111886-B2 | Polymer conjugate for delivery of a bioactive agent | PTGIS, PTGIR, PGF | TGM2 1012/4885FOLH1 1409/4885ALB 4652/4885 |
| US-20180303948-A1 | POLYMER CONJUGATE COMPRISING A BIOACTIVE AGENT | MSN, PAM, PARG | TGM2 3656/4885FOLH1 3363/4885ALB 2843/4885 |
| US-20160000929-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | PTGIS, PTGIR, PGF | TGM2 987/4885FOLH1 1105/4885ALB 4564/4885 |
| US-20170216308-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | PTGIS, PTGIR, PGF | TGM2 1012/4885FOLH1 1409/4885ALB 4652/4885 |
| US-20170182173-A1 | POLYMER CONJUGATE FOR DELIVERY OF A BIOACTIVE AGENT | PTGIS, PTGIR, PGF | TGM2 754/4885FOLH1 962/4885ALB 4760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.