Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.32 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22166724 | 0.84 | MEN1 (0.33) | LMNAGPR3ALDH1A1 | |
| SCHEMBL23352485 | 0.83 | POLB (0.33) | LMNAPSMD14POLBTHRBL3MBTL1 | |
| SCHEMBL23595205 | 0.77 | LMNA (0.32) | LMNAPSMD14GPR3POLBTHRB | |
| SCHEMBL19365233 | 0.77 | GPR3 (0.50) | LMNAGPR3POLBL3MBTL1ALDH1A1 | |
| SCHEMBL22368026 | 0.74 | ALDH1A1 (0.50) | LMNAPOLBL3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL20122222 | 0.74 | KDM4E (0.53) | L3MBTL1ALDH1A1CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL24322601 | 0.73 | ALDH1A1 (0.33) | LMNAPSMD14GPR3ALDH1A1 | |
| SCHEMBL20878494 | 0.73 | GPR3 (0.32) | LMNAPSMD14GPR3ALDH1A1 | |
| SCHEMBL22360497 | 0.73 | BCHE (0.42) | LMNAPOLBALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL23503054 | 0.73 | PSMD14 (0.33) | LMNAPSMD14POLBTHRBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3053910-B1 | ANILINE DERIVATIVES AND USES THEREOF | NISSAN CHEMICAL CORP (JP) | 2021-04-28 | — | — | EP | disclosed |