Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | F13A1 | P00488 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TGM1 | P22735 | 1/20 | 0.36 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26910352 | 0.80 | NPSR1 (0.46) | KMT2AMEN1HPGDMAPTRAB9A | |
| SCHEMBL25218588 | 0.75 | KMT2A (0.46) | ALDH1A1KMT2AKDM4EMEN1HPGD | |
| SCHEMBL25290405 | 0.73 | SLC40A1 (0.40) | ALDH1A1KDM4EHPGDADORA2AADORA1 | |
| SCHEMBL30448897 | 0.73 | ALDH1A1 (0.68) | ALDH1A1KMT2AKDM4EMEN1HPGD | |
| SCHEMBL10193856 | 0.73 | ALDH1A1 (0.68) | ALDH1A1KMT2AKDM4EMEN1HPGD | |
| SCHEMBL18489422 | 0.73 | TGM2 (0.46) | TGM2F13A1LMNATGM1TGM3 | |
| SCHEMBL1870660 | 0.72 | KMT2A (0.52) | ALDH1A1KMT2AMEN1HPGDRAB9A | |
| SCHEMBL657873 | 0.72 | ADH1B (0.41) | ALDH1A1KMT2AKDM4EHPGDMAPT | |
| SCHEMBL25600288 | 0.72 | NAMPT (0.44) | TGM2ALDH1A1MAPK1LMNAPTPN1 | |
| SCHEMBL25304631 | 0.71 | EGLN1 (0.51) | ALDH1A1KMT2AKDM4EMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3341370-B1 | CGRP RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2021-04-28 | — | — | EP | disclosed |