Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23286926 | 0.74 | PTGER4 (0.56) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL22912827 | 0.73 | CA1 (0.50) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL23559583 | 0.72 | LOXL2 (0.53) | LOXL2MAPTCA12CA1CA2 | |
| SCHEMBL23287087 | 0.72 | PTGER4 (0.43) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL13847151 | 0.71 | CA1 (0.67) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL23287088 | 0.71 | SLC7A5 (0.40) | MAPTCA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL30159680 | 0.71 | LOXL2 (0.51) | LOXL2MAPTCA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL23535841 | 0.71 | LOXL2 (0.51) | LOXL2MAPTCA12CA1CA2 | |
| SCHEMBL7920947 | 0.70 | ALDH1A1 (0.67) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL542066 | 0.70 | PRKCI (0.69) | MAPTCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021081207-A1 | GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2021-04-29 | — | — | WO | disclosed |