Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 2/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23490760 | 0.78 | PTGER4 (0.51) | SLC7A5ALOX15KDM4EGABRA1GABRG2 | |
| SCHEMBL23273557 | 0.77 | ALOX15 (0.42) | SLC7A5ALOX15CA12CA1CA2 | |
| SCHEMBL23287087 | 0.76 | PTGER4 (0.43) | CA12CA1CA2CA9CA14 | |
| SCHEMBL28754359 | 0.73 | KMT2A (0.42) | KDM4EPTGER4ALDH1A1MAPTKMT2A | |
| SCHEMBL23287036 | 0.72 | PTGER4 (0.47) | SLC7A5ALOX15CA12CA1CA2 | |
| SCHEMBL29160321 | 0.71 | ALOX15 (0.43) | SLC7A5ALOX15CA12CA1CA2 | |
| SCHEMBL24956357 | 0.71 | ALOX15 (0.43) | SLC7A5ALOX15CA12CA1CA2 | |
| SCHEMBL24083653 | 0.71 | ALOX15 (0.43) | SLC7A5ALOX15CA12CA1CA2 | |
| SCHEMBL23286840 | 0.71 | LOXL2 (0.43) | CA12CA1CA2CA9CA14 | |
| SCHEMBL30289516 | 0.70 | ALOX15 (0.51) | SLC7A5ALOX15CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021081207-A1 | GLP-1R MODULATING COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2021-04-29 | — | — | WO | disclosed |