Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23288040 | 0.81 | EGFR (0.39) | GRM5 | |
| SCHEMBL23287978 | 0.72 | PPARG (0.38) | GRM5ACACB | |
| SCHEMBL23288037 | 0.71 | FFAR1 (0.32) | — | |
| SCHEMBL25487719 | 0.69 | MTNR1A (0.44) | — | |
| SCHEMBL23287991 | 0.69 | PTGDR2 (0.35) | GRM5ACACB | |
| SCHEMBL26091012 | 0.67 | CA2 (0.46) | — | |
| SCHEMBL30349503 | 0.67 | CA2 (0.46) | — | |
| SCHEMBL15200671 | 0.66 | GRM5 (0.47) | GRM5 | |
| SCHEMBL23273761 | 0.64 | CSF1R (0.42) | GRM5 | |
| SCHEMBL4711488 | 0.64 | GRM5 (0.47) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021080013-A1 | INHIBITORS OF TREK (TWIK RELATED K+ CHANNELS) CHANNEL FUNCTION | ONO PHARMACEUTICAL CO., LTD. (JP) | 2021-04-29 | — | — | WO | disclosed |