Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26091012 | 1.00 | CA2 (0.46) | CA2CA1MTNR1AMTNR1BMEN1 | |
| SCHEMBL25487719 | 0.88 | MTNR1A (0.44) | CA2CA1MTNR1AMTNR1BMEN1 | |
| SCHEMBL10229485 | 0.82 | ALDH1A1 (0.53) | CA2CA1SIGMAR1CYP1A2CYP2D6 | |
| SCHEMBL15181144 | 0.80 | CA2 (0.46) | CA2CA1KMT2AHTTALDH1A1 | |
| SCHEMBL46585 | 0.80 | MTNR1A (0.43) | CA2CA1MTNR1AMTNR1BMEN1 | |
| SCHEMBL1829911 | 0.79 | TSHR (0.59) | TSHRL3MBTL1HPGDSMN1; SMN2 | |
| SCHEMBL28553472 | 0.79 | MTNR1A (0.51) | MTNR1AMTNR1BMEN1KMT2AHTT | |
| SCHEMBL2427540 | 0.78 | MAPT (0.56) | MTNR1AMTNR1BKMT2ACYP1A2CYP2D6 | |
| SCHEMBL1725721 | 0.78 | MTNR1A (0.45) | MTNR1AMTNR1BMEN1KMT2AHTT | |
| SCHEMBL2432439 | 0.78 | ALDH1A1 (0.45) | MTNR1AMTNR1BTSHRALOX15ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069731-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND METHODS OF USE THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | WO | disclosed |