Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17101275 | 0.89 | CHRM1 (0.41) | KDM4EOPRD1ALDH1A1CHRM2CHRM1 | |
| SCHEMBL17101500 | 0.83 | L3MBTL1 (0.32) | KDM4EL3MBTL1SMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL23289874 | 0.79 | CHRM1 (0.30) | CHRM1 | |
| SCHEMBL17101486 | 0.77 | OPRL1 (0.46) | KDM4ESMN1; SMN2OPRM1OPRD1OPRK1 | |
| SCHEMBL17101501 | 0.75 | SMN1; SMN2 (0.37) | KDM4EL3MBTL1SMN1; SMN2OPRM1OPRD1 | |
| SCHEMBL29822545 | 0.75 | SMN1; SMN2 (0.37) | KDM4EL3MBTL1SMN1; SMN2OPRM1OPRD1 | |
| SCHEMBL20942431 | 0.74 | ALDH1A1 (0.35) | KDM4EOPRD1ALDH1A1CHRM1TSHR | |
| SCHEMBL22653213 | 0.74 | OPRD1 (0.31) | KDM4EOPRD1ALDH1A1 | |
| SCHEMBL23289877 | 0.74 | OPRL1 (0.31) | OPRL1 | |
| SCHEMBL23289903 | 0.72 | OPRL1 (0.34) | OPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119396-B1 | MUSCARINIC RECEPTOR AGONISTS | HEPTARES THERAPEUTICS LTD (GB) | 2021-05-05 | — | — | EP | claimed |