SCHEMBL17101486

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18075896	0.86	SIGMAR1 (0.48)	OPRL1OPRM1OPRD1OPRK1SIGMAR1
	SCHEMBL29822545	0.81	SMN1; SMN2 (0.37)	OPRL1OPRM1OPRD1OPRK1KDM4E
	SCHEMBL17101501	0.81	SMN1; SMN2 (0.37)	OPRL1OPRM1OPRD1OPRK1KDM4E
	SCHEMBL17101341	0.79	SIGMAR1 (0.45)	OPRL1OPRM1OPRD1OPRK1SIGMAR1
	SCHEMBL23289886	0.77	TRPV6 (0.35)	OPRL1OPRM1OPRD1OPRK1SIGMAR1
	SCHEMBL17113644	0.76	OPRM1 (0.50)	OPRL1OPRM1OPRD1OPRK1SIGMAR1
	SCHEMBL17101500	0.72	L3MBTL1 (0.32)	KDM4ESMN1; SMN2ALDH1A1
	SCHEMBL17101275	0.72	CHRM1 (0.41)	OPRD1KDM4ECHRM2ALDH1A1
	SCHEMBL13864847	0.71	OPRL1 (0.48)	OPRL1OPRM1OPRD1OPRK1SIGMAR1
	SCHEMBL22653213	0.71	OPRD1 (0.31)	OPRD1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.