SCHEMBL2329154

SCHEMBL2329154

CCCC[Sn](CCCC)(CCCC)OCCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 2/20 0.43
KCNH2 Q12809 2/20 0.40
IDO1 P14902 1/20 0.40
PTGES O14684 3/20 0.39
ALOX5 P09917 3/20 0.39
PPARG P37231 3/20 0.39
CTSK P43235 1/20 0.39
MEN1 O00255 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
KMT2A Q03164 1/20 0.38
CETP P11597 1/20 0.38
CHRM2 P08172 1/20 0.38
HTR1A P08908 1/20 0.38
ADRA2A P08913 1/20 0.38
CHRM1 P11229 1/20 0.38
DRD1 P21728 1/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
ADRA1A P35348 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2359628 0.97 SIGMAR1 (0.41) SIGMAR1KCNH2IDO1PTGESALOX5
SCHEMBL2327364 0.97 SIGMAR1 (0.41) SIGMAR1KCNH2IDO1PTGESALOX5
SCHEMBL2330784 0.93 SIGMAR1 (0.41) SIGMAR1KCNH2IDO1PTGESALOX5
SCHEMBL2325552 0.93 SIGMAR1 (0.41) SIGMAR1KCNH2IDO1PTGESALOX5
SCHEMBL2324909 0.86 SIGMAR1 (0.43) SIGMAR1KCNH2IDO1PTGESALOX5
SCHEMBL2326215 0.84 SIGMAR1 (0.42) SIGMAR1KCNH2IDO1PTGESALOX5
SCHEMBL2326189 0.84 SIGMAR1 (0.42) SIGMAR1KCNH2IDO1PTGESALOX5
SCHEMBL2345050 0.83 SIGMAR1 (0.41) SIGMAR1KCNH2IDO1PTGESALOX5
SCHEMBL2326268 0.81 CETP (0.42) SIGMAR1IDO1CETP
SCHEMBL2347598 0.81 SIGMAR1 (0.40) SIGMAR1KCNH2IDO1PTGESALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1987881-B1 METHOD FOR SEPARATION AND COLLECTION OF DIALKYL TIN DIALKOXIDE ASAHI KASEI CHEMICALS CORP (JP) 2011-08-17 EP disclosed
US-7842828-B2 Method for separating out and recovering dialkyltin dialkoxide ASAHI KASEI CHEMICALS CORPORATION (JP) 2010-11-30 US disclosed
US-20100160662-A1 Method for Separating Out and Recovering Dialkyltin Dialkoxide ASAHI KASEI KABUSHIKI KAISHA (JP) 2010-06-24 US disclosed
EP-1987881-A1 METHOD FOR SEPARATION AND COLLECTION OF DIALKYL TIN DIALKOXIDE Asahi Kasei Chemicals Corporation (JP) 2008-11-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100160662-A1 Method for Separating Out and Recovering Dialkyltin Dialkoxide ALOX5, ALOX15B, ALOX15 SIGMAR1 2657/4885KCNH2 1319/4885IDO1 2152/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.