Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 5/20 | 0.52 |
| ▸ | NOS1 | P29475 | 4/20 | 0.52 |
| ▸ | NOS3 | P29474 | 2/20 | 0.52 |
| ▸ | CCNK | O75909 | 3/20 | 0.51 |
| ▸ | CDK12 | Q9NYV4 | 3/20 | 0.51 |
| ▸ | CCR6 | P51684 | 1/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | CDK7 | P50613 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23292432 | 0.88 | CCNK (0.51) | NOS2NOS1NOS3CCNKCDK12 | |
| SCHEMBL23292267 | 0.86 | CYP3A4 (0.55) | NOS2NOS1NOS3CCNKCDK12 | |
| SCHEMBL9108352 | 0.84 | NOS2 (0.70) | NOS2NOS1NOS3CCR6MAP4K4 | |
| SCHEMBL30458637 | 0.82 | NOS2 (0.46) | NOS2NOS1NOS3MAP4K4MAPT | |
| SCHEMBL595392 | 0.81 | NOS2 (0.59) | NOS2NOS1NOS3CCNKCDK12 | |
| SCHEMBL595393 | 0.81 | NOS2 (0.59) | NOS2NOS1NOS3CCNKCDK12 | |
| SCHEMBL23292281 | 0.80 | USP30 (0.54) | CCNKCDK12CCR6PDE10AMAPT | |
| SCHEMBL22895552 | 0.80 | USP30 (0.54) | CCNKCDK12CCR6PDE10AMAPT | |
| SCHEMBL28911208 | 0.80 | USP30 (0.54) | CCNKCDK12CCR6PDE10AMAPT | |
| SCHEMBL28559025 | 0.79 | CCNK (0.60) | NOS2NOS1NOS3CCNKCDK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3813819-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES | Kinnate Biopharma Inc. (US) | 2021-05-05 | — | — | EP | disclosed |