Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | CDC7 | O00311 | 1/20 | 0.30 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.30 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17827879 | 0.84 | APLNR (0.39) | DGAT1MAPTCYP2C9CYP2C19NPSR1 | |
| SCHEMBL17819533 | 0.81 | CDC7 (0.32) | DGAT1MAPTCDC7DBF4ALDH1A1 | |
| SCHEMBL17827878 | 0.81 | CDC7 (0.36) | DGAT1MAPTMEN1CYP1A2CYP2C9 | |
| SCHEMBL13278170 | 0.81 | NQO1 (0.38) | DGAT1MAPTLMNACYP1A2KMT2A | |
| SCHEMBL22265136 | 0.80 | POLB (0.45) | AGBL2POLBMAPTMEN1KMT2A | |
| SCHEMBL17819458 | 0.79 | PDXK (0.34) | DGAT1CDC7DBF4 | |
| SCHEMBL4550628 | 0.78 | BRD4 (0.39) | POLBMAPTMEN1LMNACYP1A2 | |
| SCHEMBL16036688 | 0.77 | APLNR (0.36) | DGAT1POLBMAPTMEN1LMNA | |
| SCHEMBL25405412 | 0.74 | THRB (0.41) | AGBL2MAPTMEN1CYP2C9CYP2C19 | |
| SCHEMBL17819794 | 0.73 | ALDH1A1 (0.42) | POLBMAPTLMNACYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3814326-A1 | DIHYDROPYRIMIDINE DERIVATIVES AND USES THEREOF IN THE TREATMENT OF HBV INFECTION OR OF HBV-INDUCED DISEASES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-05-05 | — | — | EP | disclosed |