SCHEMBL2329370

SCHEMBL2329370

N#CC(c1cccc(F)c1)C(CC(=O)O)c1cc(F)cc(Br)c1

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.38
HDAC7 Q8WUI4 1/20 0.38
HDAC5 Q9UQL6 1/20 0.38
FFAR1 O14842 1/20 0.37
CTSA P10619 4/20 0.37
CNR2 P34972 1/20 0.36
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
EEF2K O00418 1/20 0.34
CYP26A1 O43174 1/20 0.34
USP2 O75604 1/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10694689 0.87 CNR2 (0.43) HDAC4HDAC7HDAC5FFAR1CTSA
SCHEMBL2333767 0.86 KCNA5 (0.40) HDAC4HDAC7HDAC5CNR2ALDH1A1
SCHEMBL10452001 0.85 LMNA (0.47) HDAC4HDAC7HDAC5FFAR1CTSA
SCHEMBL11157668 0.85 CNR2 (0.43) HDAC4HDAC7HDAC5FFAR1CTSA
SCHEMBL2330078 0.84 POLB (0.35) HDAC4HDAC7HDAC5CES2CES1
SCHEMBL10452077 0.83 LMNA (0.44) HDAC4HDAC7HDAC5FFAR1CTSA
SCHEMBL15862682 0.82 CYP2C9 (0.46) FFAR1CTSACNR2CES2CES1
SCHEMBL14635509 0.82 PGR (0.41) HDAC4HDAC7HDAC5FFAR1CTSA
SCHEMBL10179071 0.81 KCNA5 (0.40) ALDH1A1HTT
SCHEMBL11157911 0.80 CTSA (0.43) CTSACYP26A1ALDH1A1HPGDHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011098417-A1 SUBSTITUTED CYANOBUTYRATES HAVING HERBICIDAL ACTION BASF SE (DE) 2011-08-18 WO disclosed