Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14236759 | 0.78 | — | — | |
| SCHEMBL2337730 | 0.74 | ASIC3 (0.34) | — | |
| SCHEMBL2334159 | 0.73 | IDO1 (0.32) | — | |
| SCHEMBL16650795 | 0.72 | JAK2 (0.35) | JAK2TYK2XDHSLC22A12 | |
| SCHEMBL2331106 | 0.71 | MCL1 (0.32) | — | |
| SCHEMBL658395 | 0.68 | TLR8 (0.54) | JAK2TYK2 | |
| SCHEMBL16651306 | 0.66 | ALDH1A1 (0.35) | JAK2TYK2 | |
| SCHEMBL27974835 | 0.62 | MAOA (0.50) | XDHSLC22A12 | |
| SCHEMBL18421043 | 0.61 | ALDH1A1 (0.38) | — | |
| SCHEMBL27834381 | 0.61 | NOS3 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8378104-B2 | 7-aminofuropyridine derivatives | OSI Pharmaceuticals, LLC (US) | 2013-02-19 | — | — | US | disclosed |
| EP-2534156-A1 | 7-AMINOFUROPYRIDINE DERIVATIVES | OSI Pharmaceuticals, LLC (US) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011100502-A1 | 7-AMINOFUROPYRIDINE DERIVATIVES | OSI Pharmaceuticals, LLC (US) | 2011-08-18 | — | — | WO | disclosed |