SCHEMBL23295247

SCHEMBL23295247

O=C(O)/C(O)=C\c1ccc(N2CCOCC2)cc1

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.58
KMT2A Q03164 4/20 0.58
MAPT P10636 10/20 0.55
ALDH1A1 P00352 7/20 0.55
SMN1; SMN2 Q16637 5/20 0.55
NPC1 O15118 4/20 0.55
RAB9A P51151 4/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
LMNA P02545 4/20 0.54
MAOB P27338 1/20 0.51
MITF O75030 1/20 0.49
KDM4E B2RXH2 5/20 0.48
GSK3B P49841 1/20 0.47
KMO O15229 1/20 0.46
POLB P06746 1/20 0.46
GAA P10253 1/20 0.46
HPGD P15428 1/20 0.46
ALOX12 P18054 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18694393 0.81 MEN1 (0.52) MEN1KMT2AMAPTALDH1A1SMN1; SMN2
SCHEMBL18694390 0.81 MEN1 (0.52) MEN1KMT2AMAPTALDH1A1SMN1; SMN2
SCHEMBL18693307 0.78 MAPT (0.68) MEN1KMT2AMAPTALDH1A1SMN1; SMN2
SCHEMBL18693305 0.78 MAPT (0.68) MEN1KMT2AMAPTALDH1A1SMN1; SMN2
SCHEMBL12306023 0.77 MEN1 (0.62) MEN1KMT2AMAPTALDH1A1SMN1; SMN2
SCHEMBL11823548 0.77 MAPT (0.71) MEN1KMT2AMAPTALDH1A1SMN1; SMN2
SCHEMBL11823556 0.77 MAPT (0.71) MEN1KMT2AMAPTALDH1A1SMN1; SMN2
SCHEMBL12526119 0.76 MEN1 (0.61) MEN1KMT2AMAPTALDH1A1SMN1; SMN2
SCHEMBL11264997 0.75 PTGS2 (0.75) MEN1KMT2AMAPTALDH1A1SMN1; SMN2
SCHEMBL28078019 0.75 PRKDC (0.53) MEN1KMT2AMAPTALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3676265-B1 METHOD FOR THE SYNTHESIS OF CYCLIC DEPSIPEPTIDES ELANCO ANIMAL HEALTH GMBH (DE) 2025-08-20 EP disclosed
US-20250019360-A1 METHOD FOR THE SYNTHESIS OF CYCLIC DEPSIPEPTIDES ELANCO ANIMAL HEALTH GMBH (DE) 2025-01-16 US disclosed
US-12122759-B2 Method for the synthesis of cyclic depsipeptides ELANCO ANIMAL HEALTH GMBH (DE) 2024-10-22 US disclosed
US-20210130315-A1 METHOD FOR THE SYNTHESIS OF CYCLIC DEPSIPEPTIDES BAYER ANIMAL HEALTH GMBH (DE) 2021-05-06 US disclosed
US-20210130315-A1 METHOD FOR THE SYNTHESIS OF CYCLIC DEPSIPEPTIDES BAYER ANIMAL HEALTH GMBH (DE) 2021-05-06 US disclosed
CN-111757880-A Method for synthesizing cyclic depsipeptides 拜耳动物保健有限责任公司 2020-10-09 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210130315-A1 METHOD FOR THE SYNTHESIS OF CYCLIC DEPSIPEPTIDES DNPEP, NPEPPS, PREP MEN1 364/4885KMT2A 4009/4885MAPT 2048/4885
US-12122759-B2 Method for the synthesis of cyclic depsipeptides DNPEP, NPEPPS, PREP MEN1 364/4885KMT2A 4009/4885MAPT 2048/4885
US-20250019360-A1 METHOD FOR THE SYNTHESIS OF CYCLIC DEPSIPEPTIDES DNPEP, NPEPPS, PREP MEN1 364/4885KMT2A 4009/4885MAPT 2048/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.