Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 5/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.42 |
| ▸ | HRH1 | P35367 | 3/20 | 0.42 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20495529 | 0.84 | ALDH1A1 (0.46) | HRH3HRH4CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL23295276 | 0.78 | PDE2A (0.42) | PPARDHRH3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14017008 | 0.77 | HPGD (0.45) | SLC6A4MAOAALDH1A1MAOB | |
| SCHEMBL7054031 | 0.77 | PTGDR2 (0.48) | HRH3CYP3A4CYP2C19CYP1A2SLC6A2 | |
| SCHEMBL19771848 | 0.76 | HRH3 (0.43) | PPARDHRH3HRH1HRH4CYP3A4 | |
| SCHEMBL9621560 | 0.76 | HRH3 (0.40) | PPARDHRH3HRH1HRH4CYP3A4 | |
| SCHEMBL23106578 | 0.76 | MAOA (0.44) | CYP3A4SLC6A4MAOAALDH1A1MAOB | |
| SCHEMBL12475094 | 0.76 | MAOA (0.63) | SLC6A4MAOAMAOB | |
| SCHEMBL24088816 | 0.75 | MAOA (0.61) | SLC6A4MAOAALDH1A1MAOB | |
| SCHEMBL13074353 | 0.75 | MAOA (0.61) | SLC6A4MAOAALDH1A1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3592729-B1 | CATALYTIC C-X-BOND METATHESIS THROUGH ARYLATION | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2021-06-30 | — | — | EP | disclosed |
| EP-3592729-B1 | CATALYTIC C-X-BOND METATHESIS THROUGH ARYLATION | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2021-06-30 | — | — | EP | disclosed |
| US-20210130286-A1 | CATALYTIC C-X-BOND METATHESIS THROUGH ARYLATION | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2021-05-06 | — | — | US | disclosed |
| US-20210130286-A1 | CATALYTIC C-X-BOND METATHESIS THROUGH ARYLATION | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210130286-A1 | CATALYTIC C-X-BOND METATHESIS THROUGH ARYLATION | AOX1, TYR, CXXC4 | PPARD 4171/4885HRH3 2433/4885HRH1 2560/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.