Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2329595 | 0.80 | KDM4E (0.33) | KDM4EAR | |
| SCHEMBL5546729 | 0.74 | SLC6A4 (0.45) | SLC6A4KDM4EHSD17B10AR | |
| SCHEMBL145124 | 0.74 | ALDH1A1 (0.52) | KDM4E | |
| SCHEMBL575613 | 0.72 | HSD17B10 (0.45) | SLC6A4KDM4EHSD17B10AR | |
| SCHEMBL21100519 | 0.72 | SLC6A4 (0.48) | SLC6A4KDM4EHSD17B10AR | |
| SCHEMBL10969374 | 0.72 | KDM4E (0.34) | KDM4E | |
| SCHEMBL11661367 | 0.72 | KDM4E (0.33) | SLC6A4KDM4EHSD17B10AR | |
| SCHEMBL13923556 | 0.70 | SLC6A4 (0.47) | SLC6A4KDM4EHSD17B10AR | |
| Fluoride SCHEMBL777953 | 0.70 | HSD17B10 (0.43) | SLC6A4KDM4EHSD17B10AR | |
| Fluoride SCHEMBL1335636 | 0.70 | HSD17B10 (0.43) | SLC6A4KDM4EHSD17B10AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7371747-B2 | Cyanoalkylamino derivatives as protease inhibitors | MERCK FROSST CANADA & CO. (CA) | 2008-05-13 | — | — | US | claimed |
| EP-1446115-B1 | CYANOALKYLAMINO DERIVATIVES AS PROTEASE INHIBITORS | MERCK FROSST CANADA LTD (CA) | 2008-02-27 | — | — | EP | claimed |
| EP-1446115-A4 | CYANOALKYLAMINO DERIVATIVES AS PROTEASE INHIBITORS | MERCK FROSST CANADA INC (CA) | 2005-02-02 | — | — | EP | claimed |
| US-20050014941-A1 | Cyanoalkylamino derivatives as protease inhibitors | MERCK FROSST CANADA LTD. (CA) | 2005-01-20 | — | — | US | claimed |
| EP-1446115-A2 | CYANOALKYLAMINO DERIVATIVES AS PROTEASE INHIBITORS | Merck Frosst Canada & Co. (CA) | 2004-08-18 | — | — | EP | claimed |
| WO-2003041649-A2 | CYANOALKYLAMINO DERIVATIVES AS PROTEASE INHIBITORS | MERCK FROSST CANADA & CO. (CA) | 2003-05-22 | — | — | WO | claimed |
| CN-112424253-B | Bulk polymerization of polyoxazolidinones | 巴斯夫欧洲公司 | 2024-02-27 | — | — | CN | disclosed |
| US-10857121-B2 | Use of malononitrile compounds for protecting animals from parasites | MERIAL INC. (US) | 2020-12-08 | — | — | US | disclosed |
| EP-3131398-B1 | USE OF MALONONITRILE COMPOUNDS FOR PROTECTING ANIMALS FROM PARASITES | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2019-10-23 | — | — | EP | disclosed |
| US-10292388-B2 | Malononitrile compounds for controlling animal pests | BASF SE (DE) | 2019-05-21 | — | — | US | disclosed |
| CN-105849206-B | Adhesive composition | 建筑研究和技术有限公司 | 2018-05-29 | — | — | CN | disclosed |
| EP-2911509-B1 | MALONONITRILE COMPOUNDS FOR CONTROLLING ANIMAL PESTS | BASF SE (DE) | 2017-07-19 | — | — | EP | disclosed |
| EP-3131398-A1 | USE OF MALONONITRILE COMPOUNDS FOR PROTECTING ANIMALS FROM PARASITES | Merial, Inc. (US) | 2017-02-22 | — | — | EP | disclosed |
| EP-0145434-A2 | Novel dihydropyridine derivatives and process for preparing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1985-06-19 | — | — | EP | disclosed |
| EP-0138754-A2 | Photocurable compositions | CIBA-GEIGY AG (CH) | 1985-04-24 | — | — | EP | disclosed |
| US-4136100-A | BLUE-VIOLET TO GREEN-BLUE DYEINGS ON CELLULOSE TEXTILES | BASF AKTIENGESELLSCHAFT (DE) | 1979-01-23 | — | — | US | disclosed |
| US-4120886-A | APHIDICIDES | PPG INDUSTRIES, INC. (US) | 1978-10-17 | — | — | US | disclosed |
| US-4056544-A | Anthraquinone compounds | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-01 | — | — | US | disclosed |
| US-4055656-A | S-ARYL-N-CYCLOALKYLTHIOLCARBAMATES | PPG INDUSTRIES, INC. (US) | 1977-10-25 | — | — | US | disclosed |
| US-3933912-A | Substituted phenylthioamidines | THE DOW CHEMICAL COMPANY (US) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014941-A1 | Cyanoalkylamino derivatives as protease inhibitors | CTSB, CTSK, CTSS | SLC6A4 3593/4885KDM4E 2838/4885HSD17B10 1832/4885 |
| US-10857121-B2 | Use of malononitrile compounds for protecting animals from parasites | MAL2, NAT1, ME1 | SLC6A4 1660/4885KDM4E 255/4885HSD17B10 673/4885 |
| US-10292388-B2 | Malononitrile compounds for controlling animal pests | MAL2, ME1, DDT | SLC6A4 2578/4885KDM4E 323/4885HSD17B10 970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.