Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.38 |
| ▸ | CTSK | P43235 | 11/20 | 0.37 |
| ▸ | CTSS | P25774 | 7/20 | 0.36 |
| ▸ | CTSB | P07858 | 3/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 2/20 | 0.33 |
| ▸ | PPIA | P62937 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7608833 | 0.88 | CTSL (0.43) | CTSLCTSKCTSSCTSBCTSD | |
| SCHEMBL27648998 | 0.86 | JAK2 (0.37) | CTSLCTSKCTSSCTSBCTSD | |
| SCHEMBL3370066 | 0.85 | CTSL (0.41) | CTSLCTSKCTSSCTSB | |
| SCHEMBL22765979 | 0.84 | P2RX7 (0.41) | CTSLCTSKCTSSCTSB | |
| SCHEMBL4418580 | 0.83 | JAK2 (0.39) | JAK2JAK1 | |
| SCHEMBL23011175 | 0.82 | DRD2 (0.36) | CTSLCTSKCTSSCTSBCTSD | |
| SCHEMBL23276791 | 0.82 | CTSL (0.39) | CTSLCTSKCTSSCTSBCTSD | |
| SCHEMBL6017523 | 0.82 | CTSL (0.36) | CTSLCTSKCTSSCTSBCTSD | |
| SCHEMBL25105395 | 0.81 | DRD2 (0.36) | CTSLCTSKDRD2CACNA1HPPIA | |
| SCHEMBL4419835 | 0.79 | JAK2 (0.37) | JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021078021-A1 | SMALL MOLECULAR COMPOUND | 嘉兴特科罗生物科技有限公司 | 2021-04-29 | — | — | WO | disclosed |
| US-20160369267-A1 | METHODS OF CREATING AND SCREENING DNA-ENCODED LIBRARIES | X-CHEM, INC. (US) | 2016-12-22 | — | — | US | disclosed |