Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | PHGDH | O43175 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14535097 | 0.87 | FAAH (0.47) | FAAHPHGDHMGLLLMNAL3MBTL1 | |
| SCHEMBL23991849 | 0.87 | FAAH (0.47) | FAAHPHGDHMGLLLMNAL3MBTL1 | |
| SCHEMBL18533863 | 0.84 | NPSR1 (0.38) | FAAHPHGDHMGLLLMNAL3MBTL1 | |
| SCHEMBL18533882 | 0.84 | MEN1 (0.32) | FAAHPHGDHMGLLLMNAL3MBTL1 | |
| SCHEMBL26243950 | 0.82 | FAAH (0.32) | FAAHPHGDHMGLLLMNAL3MBTL1 | |
| SCHEMBL24621420 | 0.81 | FAAH (0.46) | FAAHPHGDHMGLLLMNAL3MBTL1 | |
| SCHEMBL12700597 | 0.79 | FAAH (0.41) | FAAHPHGDHMGLLLMNAL3MBTL1 | |
| SCHEMBL20385022 | 0.78 | TRPM8 (0.42) | LMNAL3MBTL1CA12CA9KMT2A | |
| SCHEMBL12811441 | 0.77 | MAPT (0.33) | L3MBTL1KMT2AMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL20169266 | 0.76 | ALDH1A1 (0.38) | KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210122773-A1 | HETEROATOMIC-BASED HOLE-TRANSPORT MATERIALS | SIGMA-ALDRICH CO. LLC | 2021-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210122773-A1 | HETEROATOMIC-BASED HOLE-TRANSPORT MATERIALS | SLC43A1, SLC7A5, NES | FAAH 4690/4885PHGDH 3325/4885MGLL 4823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.