Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752915 | 0.82 | MEN1 (0.47) | MEN1KMT2AEGFRALDH1A1MAPK1 | |
| SCHEMBL23309165 | 0.78 | MEN1 (0.32) | MEN1KMT2AEGFRALDH1A1MAPK1 | |
| SCHEMBL22968430 | 0.74 | ALDH1A1 (0.40) | MEN1KMT2AEGFRALDH1A1 | |
| SCHEMBL21172194 | 0.74 | SHBG (0.38) | MEN1KMT2AEGFR | |
| SCHEMBL24168821 | 0.73 | L3MBTL1 (0.32) | — | |
| SCHEMBL21172389 | 0.70 | EGFR (0.30) | EGFR | |
| SCHEMBL3281371 | 0.69 | EGFR (0.33) | EGFRALDH1A1MAPK1 | |
| SCHEMBL3286005 | 0.69 | EGFR (0.33) | EGFRALDH1A1MAPK1 | |
| SCHEMBL21172193 | 0.69 | — | — | |
| SCHEMBL23119121 | 0.67 | CNR1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11365192-B2 | Pyridine compound substituted with azole | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2022-06-21 | — | — | US | disclosed |
| US-20210122741-A1 | PYRIDINE COMPOUND SUBSTITUTED WITH AZOLE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2021-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210122741-A1 | PYRIDINE COMPOUND SUBSTITUTED WITH AZOLE | CYP2C19, CYP4A11, CYP11B1 | MEN1 1907/4885KMT2A 813/4885EGFR 2156/4885 |
| US-11365192-B2 | Pyridine compound substituted with azole | CYP2C19, CYP4A11, CYP11B1 | MEN1 1907/4885KMT2A 813/4885EGFR 2156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.