SCHEMBL4752915

SCHEMBL4752915

CC(C)(C)c1cc(O)no1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
EGFR P00533 1/20 0.44
ALDH1A1 P00352 1/20 0.42
MAPK1 P28482 1/20 0.42
NPC1 O15118 6/20 0.41
RAB9A P51151 6/20 0.41
MAPK14 Q16539 3/20 0.40
HPGD P15428 1/20 0.39
LMNA P02545 1/20 0.39
POLB P06746 1/20 0.39
SMN1; SMN2 Q16637 4/20 0.38
HTT P42858 3/20 0.38
PKM P14618 1/20 0.38
TSHR P16473 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
RAF1 P04049 3/20 0.38
MAPK13 O15264 1/20 0.38
MAPK12 P53778 1/20 0.38
MAPK11 Q15759 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23309165 0.82 MEN1 (0.32) MEN1KMT2AEGFRALDH1A1MAPK1
SCHEMBL23309191 0.82 MEN1 (0.32) MEN1KMT2AEGFRALDH1A1MAPK1
SCHEMBL21172194 0.77 SHBG (0.38) MEN1KMT2AEGFR
SCHEMBL24168821 0.76 L3MBTL1 (0.32)
SCHEMBL84872 0.73 MEN1 (0.48) MEN1KMT2AEGFRALDH1A1MAPK1
SCHEMBL171117 0.73 KMT2A (0.48) MEN1KMT2AEGFRALDH1A1MAPK1
SCHEMBL21172389 0.73 EGFR (0.30) EGFR
SCHEMBL13230275 0.73 MEN1 (0.44) MEN1KMT2AEGFRALDH1A1MAPK1
SCHEMBL21172193 0.72
SCHEMBL22140176 0.71 MEN1 (0.47) MEN1KMT2AEGFRALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 248 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240239809-A1 THERAPEUTIC AGENTS FOR ENHANCING EPITHELIAL AND/OR ENDOTHELIAL BARRIER FUNCTION ARTUS THERAPEUTICS INC (US) 2024-07-18 US disclosed
US-20230348501-A1 HETEROARYL INHIBITORS OF PDE4 Tetra Discovery Partners, LLC 2023-11-02 US disclosed
US-11773077-B2 Compounds containing carbon-carbon linker as GPR120 agonists Piramal Enterprises Limited (IN) 2023-10-03 US disclosed
US-11767334-B2 Heteroaryl inhibitors of PDE4 Tetra Discovery Partners, LLC (US) 2023-09-26 US disclosed
US-20230279426-A1 MODIFIED VIRAL COMPOSITIONS FOR VIRAL TRANSDUCTION LYCIA THERAPEUTICS, INC. 2023-09-07 US disclosed
US-20230279426-A1 MODIFIED VIRAL COMPOSITIONS FOR VIRAL TRANSDUCTION LYCIA THERAPEUTICS, INC. 2023-09-07 US disclosed
US-20230257367-A1 NOVEL THYROID HORMONE BETA RECEPTOR AGONIST CHENGDU KANGHONG PHARMACEUTICAL CO., LTD. (CN) 2023-08-17 US disclosed
US-11713324-B2 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto NEUROCRINE BIOSCIENCES, INC. (US) 2023-08-01 US disclosed
US-11713324-B2 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto NEUROCRINE BIOSCIENCES, INC. (US) 2023-08-01 US disclosed
US-20230226214-A1 BIFUNCTIONAL BRIDGING COMPOSITIONS FOR VIRAL TRANSDUCTION LYCIA THERAPEUTICS, INC. 2023-07-20 US disclosed
US-H830-H CONTAINING A DESILVERING ACCELERATOR RELEASING COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1990-10-02 US disclosed
US-4950764-A HERBICIDES, BACTERICIDES, ANALGESICS, ANTIINFLAMMATORY AGENT FUJI PHOTO FILM CO., LTD. (JP) 1990-08-21 US disclosed
US-4942114-A FLUORESCENT, REFLECTIVE FUJI PHOTO FILM CO., LTD. (JP) 1990-07-17 US disclosed
US-4939066-A DEVELOPMENT INHIBITOR-RELEASING COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1990-07-03 US disclosed
US-4921785-A Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1990-05-01 US disclosed
US-4916047-A POLYMERIC COMPOUND RELEASING USEFUL GROUP BY REDOX PROCESS TRIGGERED BY REDUCING AGENT FUJI PHOTO FILM CO., LTD. (JP) 1990-04-10 US disclosed
US-4886736-A COUPLERS AND COMPOUND CAPABLE OF RELEASING PHOTOGRAPHICALLY USEFUL GROUP UPON REDUCTION FUJI PHOTO FILM CO., LTD. (JP) 1989-12-12 US disclosed
US-4783396-A Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1988-11-08 US disclosed
EP-0280252-A2 Silver halide photographic material and method for forming super high contrast image therewith FUJI PHOTO FILM CO., LTD. (JP) 1988-08-31 EP disclosed
EP-0220746-A2 Silver halide photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1987-05-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11773077-B2 Compounds containing carbon-carbon linker as GPR120 agonists GPR180, GPR68, GPR88 MEN1 4061/4885KMT2A 4492/4885EGFR 1520/4885
US-20230348501-A1 HETEROARYL INHIBITORS OF PDE4 PDE4A, PDE4B, PDE4C MEN1 4531/4885KMT2A 3408/4885EGFR 4836/4885
US-11713324-B2 Gonadotropin-releasing hormone receptor antagonists and methods relating thereto GNRHR, GHRHR, LHCGR MEN1 566/4885KMT2A 1468/4885EGFR 1317/4885
US-20230226214-A1 BIFUNCTIONAL BRIDGING COMPOSITIONS FOR VIRAL TRANSDUCTION HAVCR2, FCGR3B, FCGR2A MEN1 1824/4885KMT2A 3875/4885EGFR 60/4885
US-11767334-B2 Heteroaryl inhibitors of PDE4 PDE4A, PDE4B, PDE4C MEN1 4531/4885KMT2A 3408/4885EGFR 4836/4885
US-20240239809-A1 THERAPEUTIC AGENTS FOR ENHANCING EPITHELIAL AND/OR ENDOTHELIAL BARRIER FUNCTION LIPG, FABP2, EPCAM MEN1 4530/4885KMT2A 4821/4885EGFR 614/4885
US-20230257367-A1 NOVEL THYROID HORMONE BETA RECEPTOR AGONIST THRB, THRA, TSHR MEN1 1680/4885KMT2A 2510/4885EGFR 268/4885
US-20230279426-A1 MODIFIED VIRAL COMPOSITIONS FOR VIRAL TRANSDUCTION HAVCR2, ASGR1, FCGR3B MEN1 2803/4885KMT2A 3255/4885EGFR 52/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.