SCHEMBL1466022

SCHEMBL1466022

CC(=O)c1ccc2c(c1)CCCC2

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 8/20 0.67
RAB9A P51151 7/20 0.67
MAPT P10636 7/20 0.62
ALDH1A1 P00352 5/20 0.62
SMN1; SMN2 Q16637 5/20 0.54
HPGD P15428 3/20 0.54
CYP1A2 P05177 1/20 0.54
CYP2D6 P10635 1/20 0.54
CYP2C19 P33261 1/20 0.54
HSD17B1 P14061 1/20 0.53
NFKB1 P19838 2/20 0.50
NFKB2 Q00653 2/20 0.50
RELA Q04206 2/20 0.50
CTNNB1 P35222 1/20 0.49
WNT3A P56704 1/20 0.49
HTT P42858 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
SMYD3 Q9H7B4 1/20 0.47
KCNJ1 P48048 1/20 0.46
TDP1 Q9NUW8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31048932 1.00 NPC1 (0.67) NPC1RAB9AMAPTALDH1A1SMN1; SMN2
SCHEMBL9419020 0.98 NPC1 (0.65) NPC1RAB9AMAPTALDH1A1SMN1; SMN2
SCHEMBL22627409 0.98 NPC1 (0.65) NPC1RAB9AMAPTALDH1A1SMN1; SMN2
SCHEMBL33121 0.96 ALDH1A1 (0.68) NPC1RAB9AMAPTALDH1A1SMN1; SMN2
SCHEMBL21584068 0.91 NPC1 (0.67) NPC1RAB9AMAPTALDH1A1SMN1; SMN2
SCHEMBL29793289 0.91 NPC1 (0.67) NPC1RAB9AMAPTALDH1A1SMN1; SMN2
SCHEMBL27649495 0.86 ALDH1A1 (0.56) NPC1RAB9AMAPTALDH1A1SMN1; SMN2
SCHEMBL19231579 0.84 NPC1 (0.58) NPC1RAB9AMAPTALDH1A1SMN1; SMN2
SCHEMBL8384926 0.83 ALDH1A1 (0.67) NPC1RAB9AMAPTALDH1A1SMN1; SMN2
SCHEMBL13928814 0.82 NPC1 (0.56) NPC1RAB9AMAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 322 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250018078-A1 DEODORANT FRAGRANCE COMPOSITION TAKASAGO INTERNATIONAL CORPORATION (JP) 2025-01-16 US claimed
EP-4491200-A1 DEODORANT FRAGRANCE COMPOSITION Takasago International Corporation (JP) 2025-01-15 EP claimed
CN-119307317-A Deodorant perfume composition 高砂香料工业株式会社 2025-01-14 CN claimed
US-20240050335-A1 A SYNERGISTIC PERFUMING COMPOSITION FIRMENICH & CIE (CH) 2024-02-15 US claimed
US-20240043770-A1 A SYNERGISTIC PERFUMING COMPOSITION FIRMENICH & CIE (CH) 2024-02-08 US claimed
US-20230392098-A1 IMPROVED FRESHNESS IMPARTING COMPOSITIONS FIRMENICH SA (CH) 2023-12-07 US claimed
EP-4232536-A1 A SYNERGISTIC PERFUMING COMPOSITION Firmenich SA (CH) 2023-08-30 EP claimed
CN-116568786-A Synergistic perfuming composition 弗门尼舍有限公司 2023-08-08 CN claimed
EP-4208527-A1 IMPROVED FRESHNESS IMPARTING COMPOSITIONS Firmenich SA (CH) 2023-07-12 EP claimed
CN-116391022-A Improved freshness imparting compositions 弗门尼舍有限公司 2023-07-04 CN claimed
EP-2655307-B1 COMPOUNDS CAPABLE OF RELEASING FRAGRANT COMPOUNDS GIVAUDAN SA (CH) 2018-08-01 EP claimed
EP-2655307-A1 COMPOUNDS CAPABLE OF RELEASING FRAGRANT COMPOUNDS Givaudan SA (CH) 2013-10-30 EP claimed
WO-2012085287-A1 COMPOUNDS CAPABLE OF RELEASING FRAGRANT COMPOUNDS GIVAUDAN SA (CH) 2012-06-28 WO claimed
US-6939845-B2 Fragrance precursors GIVAUDAN SA (CH) 2005-09-06 US claimed
EP-1167362-B1 Fragance precursors GIVAUDAN SA (CH) 2005-05-25 EP claimed
US-6492563-B2 PROVIDES NON-VOLATILE PRECURSORS FOR VOLATILE FRAGRANT ESTERS FOR USE IN DETERGENT, A FABRIC SOFTENER, A WINDOW CLEANER, A HARD SURFACE CLEANER, AN ALL PURPOSE CLEANER, A FURNITURE POLISH, A SHAMPOO, A CONDITIONER, AN HAIRSPRAY, A COSMETIC GIVAUDAN SA (CH) 2002-12-10 US claimed
US-20020077508-A1 Fragrance precursors GIVAUDAN SA (CH) 2002-06-20 US claimed
US-20020035055-A1 Fragrance precursors GIVAUDAN SA (CH) 2002-03-21 US claimed
EP-1167362-A1 Fragance precursors Givaudan SA (CH) 2002-01-02 EP claimed
EP-1146033-A2 Fragrance precursors Givaudan SA (CH) 2001-10-17 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020077508-A1 Fragrance precursors ADH5, FAAH, CBR3 NPC1 2329/4885RAB9A 3089/4885MAPT 4053/4885
US-20020035055-A1 Fragrance precursors FAAH2, FDPS, CYP51A1 NPC1 2313/4885RAB9A 4566/4885MAPT 2981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.