Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | GABRE | P78334 | 1/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.34 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.34 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.34 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20535913 | 0.83 | PTPN1 (0.33) | PTPN1 | |
| SCHEMBL20535917 | 0.83 | PTPN1 (0.33) | PTPN1 | |
| SCHEMBL10940755 | 0.79 | CYP2C19 (0.39) | ALDH1A1CYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL16370866 | 0.78 | CYP2C19 (0.39) | ALDH1A1CYP3A4CYP2C9CYP2C19GABRP | |
| SCHEMBL30727072 | 0.78 | CYP2C19 (0.39) | ALDH1A1CYP3A4CYP2C9CYP2C19GABRP | |
| SCHEMBL17779666 | 0.78 | CYP2C19 (0.36) | ALDH1A1CYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL12526172 | 0.76 | KMT2A (0.32) | ALDH1A1CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL15563930 | 0.68 | ALDH1A1 (0.39) | ALDH1A1CYP3A4CYP2C9CYP2C19GABRP | |
| SCHEMBL14635820 | 0.67 | CYP2C19 (0.40) | ALDH1A1CYP3A4CYP2C9CYP2C19POLB | |
| SCHEMBL4429302 | 0.67 | PARP1 (0.36) | ALDH1A1CYP3A4CYP2C19POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220079924-A1 | GLUCOCORTICOID RECEPTOR MODULATORS | ORIC PHARMACEUTICALS, INC. | 2022-03-17 | — | — | US | disclosed |
| US-20210122730-A1 | GLUCOCORTICOID RECEPTOR MODULATORS | ORIC PHARMACEUTICALS, INC. | 2021-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210122730-A1 | GLUCOCORTICOID RECEPTOR MODULATORS | NR3C1, NR3C2, NR5A1 | ALDH1A1 3599/4885CYP3A4 1179/4885CYP2C9 2280/4885 |
| US-20220079924-A1 | GLUCOCORTICOID RECEPTOR MODULATORS | NR3C1, NR3C2, NR5A1 | ALDH1A1 3599/4885CYP3A4 1179/4885CYP2C9 2280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.