Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20535917 | 1.00 | PTPN1 (0.33) | PTPN1 | |
| SCHEMBL23311802 | 0.83 | ALDH1A1 (0.36) | PTPN1 | |
| SCHEMBL8859121 | 0.75 | PTPN1 (0.31) | PTPN1 | |
| SCHEMBL6911849 | 0.74 | PTPN1 (0.31) | PTPN1 | |
| SCHEMBL17767263 | 0.74 | PTPN1 (0.31) | PTPN1 | |
| SCHEMBL12526172 | 0.70 | KMT2A (0.32) | — | |
| SCHEMBL8357539 | 0.68 | TACR1 (0.48) | — | |
| SCHEMBL20347452 | 0.68 | HSD11B1 (0.31) | — | |
| SCHEMBL9981990 | 0.66 | METAP2 (0.30) | — | |
| SCHEMBL17775400 | 0.66 | PTPN1 (0.31) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210122730-A1 | GLUCOCORTICOID RECEPTOR MODULATORS | ORIC PHARMACEUTICALS, INC. | 2021-04-29 | — | — | US | disclosed |
| EP-3609872-A1 | GLUCOCORTICOID RECEPTOR MODULATORS | Oric Pharmaceuticals, Inc. (US) | 2020-02-19 | — | — | EP | disclosed |
| WO-2018191283-A1 | GLUCOCORTICOID RECEPTOR MODULATORS | ORIC PHARMACEUTICALS, INC. (US) | 2018-10-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210122730-A1 | GLUCOCORTICOID RECEPTOR MODULATORS | NR3C1, NR3C2, NR5A1 | PTPN1 1024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.