SCHEMBL23312079

SCHEMBL23312079

c1csc(-c2ccc3cc4cc5cc(-c6cccs6)ccc5cc4cc3c2)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.57
KCNH2 Q12809 1/20 0.57
LTA4H P09960 1/20 0.48
ERN1 O75460 1/20 0.47
RPS6KB2 Q9UBS0 2/20 0.46
KDM4E B2RXH2 2/20 0.45
MAPT P10636 2/20 0.45
SLC6A11 P48066 1/20 0.45
HDAC1 Q13547 4/20 0.44
HDAC2 Q92769 4/20 0.44
CYP3A4 P08684 2/20 0.44
CYP17A1 P05093 2/20 0.44
CYP2E1 P05181 1/20 0.44
CYP2A6 P11509 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2B6 P20813 1/20 0.44
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10013481 1.00 PGR (0.57) PGRKCNH2LTA4HERN1RPS6KB2
SCHEMBL11073783 0.96 PGR (0.54) PGRKCNH2LTA4HERN1RPS6KB2
SCHEMBL7218287 0.96 KCNH2 (0.61) PGRKCNH2LTA4HERN1RPS6KB2
SCHEMBL26259864 0.93 PGR (0.59) PGRKCNH2LTA4HERN1RPS6KB2
SCHEMBL23312119 0.92 LTA4H (0.50) PGRKCNH2LTA4HERN1RPS6KB2
SCHEMBL5518925 0.89 PGR (0.56) PGRKCNH2LTA4HERN1RPS6KB2
SCHEMBL18770051 0.89 PGR (0.56) PGRKCNH2LTA4HERN1RPS6KB2
SCHEMBL12278215 0.89 PGR (0.49) PGRKCNH2LTA4HERN1RPS6KB2
SCHEMBL5574879 0.87 PGR (0.46) PGRKCNH2LTA4HERN1RPS6KB2
SCHEMBL14379746 0.87 PGR (0.46) PGRKCNH2LTA4HERN1RPS6KB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021078217-A1 TETRACENE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF 中国科学院化学研究所 2021-04-29 WO disclosed