SCHEMBL5518925

SCHEMBL5518925

c1csc(-c2ccc3ccccc3c2)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.56
KCNH2 Q12809 1/20 0.55
RPS6KB2 Q9UBS0 1/20 0.53
KDM4E B2RXH2 3/20 0.47
MAPT P10636 2/20 0.47
NPC1 O15118 2/20 0.47
ALDH1A1 P00352 2/20 0.47
RAB9A P51151 2/20 0.47
HSD17B10 Q99714 1/20 0.47
LTA4H P09960 1/20 0.47
ERN1 O75460 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
AR P10275 1/20 0.46
NFKB1 P19838 1/20 0.46
GFER P55789 1/20 0.46
NFKB2 Q00653 1/20 0.46
RELA Q04206 1/20 0.46
GSTP1 P09211 1/20 0.45
ESR1 P03372 1/20 0.45
ESR2 Q92731 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18770051 1.00 PGR (0.56) PGRKCNH2RPS6KB2KDM4EMAPT
SCHEMBL11073783 0.94 PGR (0.54) PGRKCNH2RPS6KB2KDM4EMAPT
SCHEMBL7218287 0.94 KCNH2 (0.61) PGRKCNH2RPS6KB2KDM4EMAPT
SCHEMBL29943976 0.93 PGR (0.50) PGRKCNH2RPS6KB2KDM4EMAPT
SCHEMBL26259864 0.91 PGR (0.59) PGRKCNH2RPS6KB2KDM4EMAPT
SCHEMBL23312079 0.89 PGR (0.57) PGRKCNH2RPS6KB2KDM4EMAPT
SCHEMBL10013481 0.89 PGR (0.57) PGRKCNH2RPS6KB2KDM4EMAPT
SCHEMBL10719149 0.87 RPS6KB2 (0.46) PGRKCNH2RPS6KB2KDM4EMAPT
SCHEMBL14982718 0.87 RPS6KB2 (0.46) PGRKCNH2RPS6KB2KDM4EMAPT
SCHEMBL13311135 0.87 PGR (0.46) PGRKCNH2RPS6KB2KDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119101046-B 3-Naphthyl thiophene derivative, and preparation method and application thereof SHENYANG PHARMACEUTICAL UNIVERSITY (CN) 2026-05-26 CN claimed
CN-119101046-A 3-Naphthyl thiophene derivative, and preparation method and application thereof 沈阳药科大学 2024-12-10 CN claimed
CN-115814955-A Zinc collector for improving recovery rate of zinc and rare metal germanium and beneficiation method 广东省科学院资源利用与稀土开发研究所 2023-03-21 CN claimed
CN-115466294-A High stereoselectivity synthetic method of 2-deoxy-thioglycoside 三峡大学 2022-12-13 CN claimed
CN-114749282-A Calcium molybdate sulfuration flotation method 西安建筑科技大学 2022-07-15 CN claimed
CN-114478609-A Method for applying thiophenol photocatalyst to defluorination alkylation or defluorination protonation reaction 中国科学技术大学 2022-05-13 CN claimed
CN-108562674-B Method for measuring mesylate by derivatization HPLC-UV method 淄博职业学院 2021-06-15 CN claimed
EP-0671454-B1 Process for removal of heteroatoms EXXON RESEARCH ENGINEERING CO (US) 2000-09-06 EP claimed
US-5611915-A Process for removal of heteroatoms under reducing conditions in supercritical water EXXON RESEARCH AND ENGINEERING COMPANY (US) 1997-03-18 US claimed
EP-0671454-A2 Process for removal of heteroatoms EXXON RESEARCH AND ENGINEERING COMPANY (US) 1995-09-13 EP claimed
WO-2024235507-A1 METHOD FOR PRODUCING A POLYMER, IN PARTICULAR FOR A MEMBRANE, POLYMER, MEMBRANE AND USE OF A MEMBRANE Forschungszentrum Jülich GmbH (DE) 2024-11-21 WO disclosed
WO-2024162063-A1 AQUEOUS DISPERSION AND RESIN FILM FORMED FROM SAID AQUEOUS DISPERSION 住友化学株式会社 2024-08-08 WO disclosed
WO-2024031242-A1 METHOD FOR SYNTHESIZING ARYL BENZYL THIOETHER COMPOUND 苏州大学 2024-02-15 WO disclosed
US-20230287262-A1 PHOTON UPCONVERSION COMPOSITION, FILM, METHOD FOR CONVERTING VISIBLE LIGHT INTO ULTRAVIOLET LIGHT, AND COMPOUND KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) 2023-09-14 US disclosed
CN-115814955-A Zinc collector for improving recovery rate of zinc and rare metal germanium and beneficiation method 广东省科学院资源利用与稀土开发研究所 2023-03-21 CN disclosed
EP-0261837-A2 Electrically conductive material and a process for the preparation of same and secondary battery using the electrically conductive material Sanyo Electric Co., Ltd (JP) 1988-03-30 EP disclosed
EP-0222343-A2 Recording material FUJI PHOTO FILM CO., LTD. (JP) 1987-05-20 EP disclosed
US-4440893-A ETHYLENE HOMO OR COPOLYMER, IIA OR IIB OXIDE, AND ACETYLENE PEROXIDE COMPOUND PHILLIPS PETROLEUM COMPANY (US) 1984-04-03 US disclosed
US-4301063-A ETHYLENE HOMOPOLYMER AND COPOLYMERS UNION CARBIDE CORPORATION (US) 1981-11-17 US disclosed
US-3974114-A CALCIUM AND LITHIUM STEARATE UNION CARBIDE CORPORATION (US) 1976-08-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230287262-A1 PHOTON UPCONVERSION COMPOSITION, FILM, METHOD FOR CONVERTING VISIBLE LIGHT INTO ULTRAVIOLET LIGHT, AND COMPOUND NUDC, CCNL2, SPIN3 PGR 1192/4885KCNH2 791/4885RPS6KB2 4195/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.