SCHEMBL10013481

SCHEMBL10013481

c1csc(-c2ccc3cc4cc(-c5cccs5)ccc4cc3c2)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.57
KCNH2 Q12809 1/20 0.57
LTA4H P09960 1/20 0.48
ERN1 O75460 1/20 0.47
RPS6KB2 Q9UBS0 2/20 0.46
KDM4E B2RXH2 2/20 0.45
MAPT P10636 2/20 0.45
SLC6A11 P48066 1/20 0.45
HDAC1 Q13547 4/20 0.44
HDAC2 Q92769 4/20 0.44
CYP3A4 P08684 2/20 0.44
CYP17A1 P05093 2/20 0.44
CYP2E1 P05181 1/20 0.44
CYP2A6 P11509 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2B6 P20813 1/20 0.44
MEN1 O00255 1/20 0.43
ALDH1A1 P00352 1/20 0.43
HPGD P15428 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23312079 1.00 PGR (0.57) PGRKCNH2LTA4HERN1RPS6KB2
SCHEMBL11073783 0.96 PGR (0.54) PGRKCNH2LTA4HERN1RPS6KB2
SCHEMBL7218287 0.96 KCNH2 (0.61) PGRKCNH2LTA4HERN1RPS6KB2
SCHEMBL26259864 0.93 PGR (0.59) PGRKCNH2LTA4HERN1RPS6KB2
SCHEMBL23312119 0.92 LTA4H (0.50) PGRKCNH2LTA4HERN1RPS6KB2
SCHEMBL5518925 0.89 PGR (0.56) PGRKCNH2LTA4HERN1RPS6KB2
SCHEMBL18770051 0.89 PGR (0.56) PGRKCNH2LTA4HERN1RPS6KB2
SCHEMBL12278215 0.89 PGR (0.49) PGRKCNH2LTA4HERN1RPS6KB2
SCHEMBL5574879 0.87 PGR (0.46) PGRKCNH2LTA4HERN1RPS6KB2
SCHEMBL14379746 0.87 PGR (0.46) PGRKCNH2LTA4HERN1RPS6KB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9034439-B2 Synthesis and applications of soluble pentacene precursors and related compounds ACADEMIA SINICA (TW) 2015-05-19 US disclosed
US-9034439-B2 Synthesis and applications of soluble pentacene precursors and related compounds ACADEMIA SINICA (TW) 2015-05-19 US disclosed
US-20130017497-A1 SYNTHESIS AND APPLICATIONS OF SOLUBLE PENTACENE PRECURSORS AND RELATED COMPOUNDS ACADEMIA SINICA (TW) 2013-01-17 US disclosed
US-20130017497-A1 SYNTHESIS AND APPLICATIONS OF SOLUBLE PENTACENE PRECURSORS AND RELATED COMPOUNDS ACADEMIA SINICA (TW) 2013-01-17 US disclosed
EP-2482355-A1 Thin film transistor comprising novel conductor and dielectric compositions E. I. du Pont de Nemours and Company (US) 2012-08-01 EP disclosed
EP-2482354-A1 Thin film transistor comprising novel conductor and dielectric compositions E. I. du Pont de Nemours and Company (US) 2012-08-01 EP disclosed
US-8148543-B2 A benzene or polycondensed aromatic ring substituted with substituted thiazole groups; storage stability and high ON current CANON KABUSHIKI KAISHA (JP) 2012-04-03 US disclosed
US-8148543-B2 A benzene or polycondensed aromatic ring substituted with substituted thiazole groups; storage stability and high ON current CANON KABUSHIKI KAISHA (JP) 2012-04-03 US disclosed
US-8053840-B2 Thin film transistor comprising novel conductor and dielectric compositions E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-11-08 US disclosed
US-8053840-B2 Thin film transistor comprising novel conductor and dielectric compositions E. I. DU PONT DE NEMOURS AND COMPANY (US) 2011-11-08 US disclosed
US-7528448-B2 Thin film transistor comprising novel conductor and dielectric compositions E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-05-05 US disclosed
US-20080210933-A1 SUBSTITUTED ANTHRACENES AND ELECTRONIC DEVICES CONTAINING THE SUBSTITUTED ANTHRACENES E. I. DU PONT DE NEMOURS AND COMPANY 2008-09-04 US disclosed
US-20080210933-A1 SUBSTITUTED ANTHRACENES AND ELECTRONIC DEVICES CONTAINING THE SUBSTITUTED ANTHRACENES E. I. DU PONT DE NEMOURS AND COMPANY 2008-09-04 US disclosed
US-20080087884-A1 ORGANIC SEMICONDUCTOR MATERIAL AND ORGANIC THIN-FILM TRANSISTOR CANON KABUSHIKI KAISHA (JP) 2008-04-17 US disclosed
US-20080087884-A1 ORGANIC SEMICONDUCTOR MATERIAL AND ORGANIC THIN-FILM TRANSISTOR CANON KABUSHIKI KAISHA (JP) 2008-04-17 US disclosed
US-7355199-B2 Substituted anthracenes and electronic devices containing the substituted anthracenes E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-04-08 US disclosed
US-7355199-B2 Substituted anthracenes and electronic devices containing the substituted anthracenes E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-04-08 US disclosed
WO-2008010983-A2 THIN FILM TRANSISTOR COMPRISING NOVEL CONDUCTOR AND DIELECTRIC COMPOSITIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-01-24 WO disclosed
US-20080012006-A1 Thin film transistor comprising novel conductor and dielectric compositions E. I. DU PONT DE NEMOURS AND COMPANY 2008-01-17 US disclosed
US-20080012006-A1 Thin film transistor comprising novel conductor and dielectric compositions E. I. DU PONT DE NEMOURS AND COMPANY 2008-01-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080087884-A1 ORGANIC SEMICONDUCTOR MATERIAL AND ORGANIC THIN-FILM TRANSISTOR SLC19A2, TCP1, TTI1 PGR 2943/4885KCNH2 561/4885LTA4H 3455/4885
US-20130017497-A1 SYNTHESIS AND APPLICATIONS OF SOLUBLE PENTACENE PRECURSORS AND RELATED COMPOUNDS HVCN1, DHPS, HCN1 PGR 1824/4885KCNH2 365/4885LTA4H 1699/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.