Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 15/20 | 0.66 |
| ▸ | METTL3 | Q86U44 | 14/20 | 0.66 |
| ▸ | ADK | P55263 | 3/20 | 0.64 |
| ▸ | ATG7 | O95352 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28713523 | 0.87 | METTL3 (0.60) | PRMT5METTL3ADK | |
| SCHEMBL29365731 | 0.87 | METTL3 (0.60) | PRMT5METTL3ADK | |
| SCHEMBL29772278 | 0.80 | PRMT5 (1.00) | PRMT5METTL3 | |
| SCHEMBL23273846 | 0.80 | PRMT5 (1.00) | PRMT5METTL3 | |
| SCHEMBL381959 | 0.80 | NT5E (0.69) | — | |
| SCHEMBL21999782 | 0.80 | NT5E (0.69) | — | |
| SCHEMBL23313159 | 0.79 | PRMT5 (1.00) | PRMT5METTL3 | |
| SCHEMBL16242266 | 0.78 | ADK (0.55) | PRMT5METTL3ADK | |
| SCHEMBL8523600 | 0.78 | ADK (1.00) | ADK | |
| SCHEMBL8975530 | 0.78 | ADK (0.78) | PRMT5METTL3ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021079196-A9 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC (US) | 2022-07-14 | — | — | WO | disclosed |
| WO-2021079196-A2 | METTL3 MODULATORS | ACCENT THERAPEUTICS, INC (US) | 2021-04-29 | — | — | WO | disclosed |